The importance of understanding indoor microbial exposure is increasingly recognized, particularly concerning the emergence of pathogens and antimicrobial resistance. With the advancements of sequencing technologies, our capability of exploring indoor microbial communities has dramatically increased. However, huge challenges remain to translate sequence-based knowledge to actionable interpretations to support human health...
The importance of understanding indoor microbial exposure is increasingly recognized, particularly concerning the emergence of pathogens and antimicrobial resistance. With the advancements of sequencing technologies, our capability of exploring indoor microbial communities has dramatically increased. However, huge challenges remain to translate sequence-based knowledge to actionable interpretations to support human health...
Cite this article: Shen, J., McFarland, A.G., Blaustein, R.A. et al. An improved workflow for accurate and robust healthcare environmental surveillance using metagenomics. Microbiome 10, 206 (2022). https://doi.org/10.1186/s40168-022-01412-x and Background: Effective surveillance of microbial communities in the healthcare environment is increasingly important in infection prevention. Metagenomics-based techniques are promising due to their untargeted nature but are currently challenged by several limitations: (1) they are not powerful enough to extract valid signals out of the background noise for low-biomass samples,...