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Filtering by: Creator Billingham, Leah Katherine Resource type Dissertation Subject Biology

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Description:: The NLRP3 inflammasome is a multi-protein complex that drives sterile and pathogen-dependent inflammation. Activation of the NLRP3 inflammasome occurs in two steps: priming and activation. Priming occurs in response to an inflammatory stimulus, such as LPS. LPS-primed macrophages are subsequently activated by a second stimuli, most of which require K+...
Keyword:: macrophage, mitochondria, immunometabolism, inflammasome, and metabolism
Subject:: Biology
Creator:: Billingham, Leah Katherine
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 06/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15953 and etdadmin_upload_882213

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