Limit your search
Search Constraints
Number of results to display per page
Search Results
-
- Description:
- RNA repair pathways exist in all three domains of life. In eukaryotes, they play key roles in fundamental biological processes such as tRNA splicing and endoplasmic reticulum (ER) stress induced noncanonical splicing of a master transcription factor mRNA (named XBP1 in mammalian cells). Even though most living organisms contain an...
- Subject:
- Molecular biology
- Creator:
- Unlu, Irem
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14703 and etdadmin_upload_667262
-
- Description:
- A fundamental goal in biology is to understand how distinct cell types containing the same genetic information arise from a single stem cell throughout development. Sex determination is a key developmental process that requires a unidirectional commitment of an initially bipotential gonad towards either the male or female fate. This...
- Keyword:
- enhancers, sex reversal, CBX2, chromatin, bivalent chromatin, and sex determination
- Subject:
- Developmental biology
- Creator:
- Garcia-Moreno, Sara A. Alexandra
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_616325 and http://dissertations.umi.com/northwestern:14397
-
- Description:
- Additive manufacturing (AM) processes have advanced rapidly over the last three decades to the point where they have the potential to fundamentally change the way complex parts will be designed and fabricated in the future. Additive methods leverage the ability to join metal particles or molten droplets in a layer-by-layer...
- Keyword:
- Hydrodynamic, Thermal, Laser Induced Forward Transfer, and Aperture
- Subject:
- Mechanics, Mechanical engineering, and Civil engineering
- Creator:
- Zhang, Li
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_618185 and http://dissertations.umi.com/northwestern:14414
-
- Description:
- Two recent developments in the transportation industry – shared-use mobility services and fully-autonomous vehicles (AVs) – have the potential to fundamentally transform urban mobility. Shared-use mobility services (e.g. Uber, Lyft, Via, Chariot, ZipCar, and Car2go) are already beginning to bridge the gap between personal vehicles and fixed-route transit service in...
- Keyword:
- Dynamic Vehicle Routing, Stochastic Dynamic Control Problem, Mobility-on-Demand, Shared Mobility, and Autonomous Vehicles
- Subject:
- Transportation, Operations research, and Urban planning
- Creator:
- Hyland, Michael Francis
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14470 and etdadmin_upload_627240
-
- Description:
- Connected and automated vehicle (CAV) technology is a disruptive transportation development with potentially transformative impacts on society and the economy. CAV systems promise to significantly reduce human-caused road crashes, improve traffic flow performance, and lower pollutant emissions. However, realizing those benefits requires strategic planning for the deployment of CAV systems...
- Keyword:
- Speed Harmonization, Connected and Automated Vehicles, Shockwave Detection, and Machine Learning
- Subject:
- Transportation
- Creator:
- Elfar, Amr
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14667 and etdadmin_upload_662894
-
- Description:
- The heart of computational materials science lies in providing fundamental insights and understanding of materials behavior and properties across different scales. The significance of this task is highlighted by the Materials Genome Initiative and the emergence of computational tools and frameworks such as materials by design, microstructure sensitive design, and...
- Keyword:
- random Process, Multiscale simulation, Microstructure, Gaussian process, and Uncertainty
- Subject:
- Materials Science, Statistics, and Mechanical engineering
- Creator:
- Bostanabad, Ramin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14508 and etdadmin_upload_638165
-
- Description:
- People pursuing important goals are known to prefer means that are highly instrumental (those most likely to facilitate goal pursuit). The self-handicapping literature demonstrated an important caveat to this principle—that people instead prefer impediments (rather than instrumental means) to their most important, identity-central goals when they anticipate goal failure. Such...
- Keyword:
- Identity, Self-sabotaging, Goals, Instrumentality, and Self-handicapping
- Subject:
- Marketing
- Creator:
- Gamlin, Jessica Erin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14585 and etdadmin_upload_659968
-
- Description:
- Valence-to-core (vtc) x-ray emission spectra (XES) provides direct information on occupied valence orbitals and is sensitive to chemical environment. Combining with element specificity and high penetration of hard x-rays, it is emerging as an information-rich technique and its applications have been demonstrated in research fields, such as catalysis and metalloenzymes....
- Keyword:
- laser-pump/x-ray-probe, compound refractive lenses, spin crossover, pink beam, x-ray emission spectroscopy, and valence to core
- Subject:
- Physics
- Creator:
- Tu, Ming-Feng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_662434 and http://dissertations.umi.com/northwestern:14640
-
- Description:
- Recovering three-dimensional (3D) structural information of a specimen from a single two-dimensional (2D) measurement remains an important but challenging task in microscopic imaging. A conventional 2D microscopic image has a shallow depth-of-focus (DoF). Thus, recovering 3D information usually requires sequentially z-scanning the focal planes. This process is time consuming and...
- Keyword:
- Microscopy, Single-shot, Computational imaging, and Optimization
- Subject:
- Computer science
- Creator:
- He, Kuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_680840 and http://dissertations.umi.com/northwestern:14776
-
- Description:
- Nucleic acids not only are the building blocks of life but also a class of attractive macromolecular therapeutics. However, the delivery of therapeutic oligonucleotides into cells has been a major challenge due to their large size and highly negatively charged backbone. Spherical nucleic acids (SNAs) are a class of emerging...
- Keyword:
- Nanomedicine, Gene regulation, and Drug delivery
- Subject:
- Materials Science, Biomedical engineering, and Chemical engineering
- Creator:
- Zhu, Shengshuang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_672179 and http://dissertations.umi.com/northwestern:14728