Drawing from the data I collected through nine months (between 2014 to 2017) of participant observations, 120 in-depth, semi-structured interviews, and archival work, the project explores the tactics that Chechen and Dagestani journalists utilize to resist state pressure and circumvent state-imposed censorship. Specifically, I explicate how these regional journalists in...
We live in an increasingly computational world; one that, in the near term, may require everyone to be computationally literate. Computer science (CS) education has greatly increased its reach in the last two decades with an increasing number of students having access to formal computer science classroom experiences in the...
This dissertation is an ethnographic study of the dance makerspace, a learning environment designed to support STEM engagement through making and embodied experience for a group of African American youth dancers. It looks at how participants in a 4-week summer camp program at an urban creative arts center-turned-makerspace, constructed embodied...
Drawing on archival research and a new attention to literary form, Sion’s Muse argues that the religious poetry of the English Reformation decisively constituted new modes of devotional affect for laypeople. At the beginning of the English Reformation, the psalm translator Miles Coverdale wrote, “Would God that our minstrels had...
Within scholarship on mid-century Hollywood musicals, celebrity, glamour, and spectacle are commonly included in the conversation about the films themselves. Yet, what happened when these films – which privilege visuality – were adapted into purely aural forms, has not been as deeply analyzed. In this project, I track the cross-media...
Economic inequality has reached historically high levels in both the United States and in the world. The research literature in sociology and political science has long shown that individuals tend to be very persistent in their views on the determinants of economic success, although these views may be formed on...
Neurodegenerative diseases (NDs) commonly involve the accumulation and aggregation of neurotoxic proteins that impair and ultimately destroy specific neurons. Considerable evidence from human and animal studies indicates that many NDs show disrupted circadian and sleep as symptoms. Yet little is known about the molecular mechanisms by which genes cause NDs...
Dystonia is a movement disorder characterized by involuntary and repetitive co-contractions of the agonist and antagonist muscles. Dystonia 6 (DYT6) is an autosomal dominant dystonia caused by loss of function mutations in the zinc finger transcription factor THAP1. I have generated Thap1 knock-out mice with a view to understanding its...
The Brink-Schwarz superparticle is a one-dimensional analogue of the Green-Schwarz superstring. In this thesis, we use the Batalin-Vilkovisky formalism to study the superparticle. After proving a vanishing result for its Batalin-Vilkovisky cohomology, we explain the sense in which the superparticle exhibits general covariance in the world-line. Using techniques from rational...
Spinal cord injury (SCI) is a devastating injury, which can be caused by motor vehicle accidents, violence, and non-traumatic causes. These injuries can leave patients with lifelong paralysis, as well as incontinence and life threatening autonomic dysreflexia. There is currently no FDA approved treatment for SCI. Spinal injury disrupts the...
Developing materials with comparable structural complexity and programmed hierarchy as those found in nature is a grand challenge in materials science. One way to synthesize soft materials with these complex architectures is to use bottom-up self-assembly of nanoscale building blocks, mimicking how organisms grow tissues with specific functions from peptides,...
Bio-inspired materials have a distinct advantage over other materials by virtue of their mimicry of nature’s own products, which have been subjected to the inimitable tests of time and evolutionary pressure. Here we have taken instruction from natural nanostructures that are ubiquitous across the animal kingdom, namely high-density lipoproteins (HDL)....
This dissertation, titled “Empire of Ruins: France in Roman Africa, 1830-1900,” explores the relationship between French colonialism in Algeria and Tunisia and the study of Roman Africa in the nineteenth century. Its central argument is that the French study and use of Roman ruins produced a version of Roman history...
Carbonates constitute Earth's largest carbon (C) reservoir, with most shallow marine deposition occurring on the low-latitude carbonate platforms covering ~800,000 km2. The Yucatán Platform situated between the Western Caribbean and Gulf of Mexico basins, is one of the largest present-day carbonate platforms. As with post-Paleozoic carbonates generally, it is readily...
Speech recognition in complex acoustic environments is dependent on myriad bottom-up (i.e., peripheral) and top-down (i.e., central) processes. While bottom-up processes remain fairly stable during childhood, the development of top-down processes persists into young adulthood. The immaturity of top-down processes places younger children at considerable risk for poorer speech recognition...
Optimization via simulation (OvS) is the practice of minimizing or maximizing the expected value of the output of a stochastic simulation model with respect to controllable decision variables. Stochastic simulation is a standard tool within operations research and is often required to model complex systems subject to uncertainty where it...
The increasing demand for green energy has created great demand for high purity lanthanide elements because of their wide range of applications, such as in permanent magnets, batteries, and high-energy capacitors. Solvent extraction, which transfers ions from aqueous solutions to organic liquid phases with the support of extractant molecules, is...
Proper partitioning of mitochondria and mtDNA is critical for cellular health. Investigations into mitochondrial inheritance, specifically how mtDNA inheritance is coupled with the inheritance mitochondrial compartment, are still in the early stages. We use budding yeast as a model polarized cell system to study a mitochondrial Myo2-adaptor protein, Mmr1, in...
This dissertation investigates the use of organic and semiconductor nanomaterials as chromophores in solar fuels production and energy transfer-mediated [2+2] cycloadditions. A series of novel N-annulated perylene chromophore amphiphiles was synthesized via a modular synthesis. These perylene amphiphiles were found to self-assemble in aqueous solution, forming extended ribbon-like nanostructures that...
The study and design of machines that are able to analyze the auditory scene and organize sound into parts that are perceptually meaningful to humans is referred to as machine hearing. Such machines are expected to distinguish between different sound categories (e.g., speech, music, background noise), focus on a sound...
Imagine sitting in a room listening to some friends play a song. Perhaps one friend is playing guitar, another playing bass, and a third is playing drums. The musical content in this scene is extraordinarily complex, yet it contains many types of structure that is easy for us to comprehend....
In the late 2000’s, scientific studies in cultural heritage saw a great advancement in macro X-ray fluorescence (XRF) imaging of paintings. These images are used to generate elemental distribution maps, which aid in identifying chemical elements and paint pig- ments as well as their locations throughout the layers of the...
We consider data-driven approaches for universal texture modeling via generative adversarial networks and inversion methods. We investigate the properties of the learned representation spaces and demonstrate that a strong link between texture analysis and synthesis is the key to successful texture modeling. First, we visit the problem of texture synthesis...
Location-aware technologies, such as personal navigation applications, location-based AR games, and artificial intelligence systems that learn from data about places, increasingly mediate our understanding of and interactions with the world. However, a number of risks associated with location-aware technologies have emerged, jeopardizing the welfare of its users. This dissertation seeks...
Recent advancements in processing and manufacturing techniques have spurred an exponential increase in use of polymer nanocomposites in a variety of applications. A key challenge in using these nanocomposites effectively is the dispersion of nanoparticles in the polymer matrix. Matrix-free assemblies of polymer grafted nanoparticles, called hairy nanoparticles assemblies(aHNPs) have...
Intelligence in humans is largely characterized by the ability to encode information into compressible representations to facilitate efficient communication for collaboration and learning. The goal of this thesis is to enable robots to both learn and act on compressible representations in real-time. I show how active exploration with respect to...
While optimization has received much attention in the machine learning community, most of them consider unconstrained supervised learning models such as neural networks and support vector machine. In this dissertation, we introduce a new class of optimization problems called scale invariant problems that include interesting unsupervised learning models such as...
This thesis focuses on applications of recurrent neural networks (RNNs) for three aspects of sequential classification. In the first chapter, a novel method to generate synthetic minority data generation to improve imbalanced classification is discussed. Generative Adversarial Networks (GANs) have been used in many different applications to generate realistic synthetic...
Previous studies have documented a systematic discrepancy between probabilistic seismic hazard maps and historical records of shaking (Stein et al., 2015; Brooks et al., 2016, 2017, 2018, 2019; Salditch et al., 2020; Salditch, 2021). In almost every case, shaking predicted by the hazard map is higher than that historically observed....
Pragmatic language, or the use of language in social contexts, is critical to developing meaningful social relationships and is a significant contributor to mental health. Autism spectrum disorder (ASD), fragile X syndrome (FXS) and Down syndrome (DS) are all genetically based neurodevelopmental disabilities characterized by deficits in pragmatic language, although...
Segregation of polydisperse granular materials remains to be a challenging problem in many industrial processes. However, most studies have focused either on bidisperse (two different particle size species) materials, which are not representative of most real mixtures, or on polydisperse materials in an idealized simple geometry. Additionally, most studies have...
One of the central challenges in solid-state chemistry is synthetic control over structure. Owing to limited reactivity of Pb with transition metals at ambient pressure and high temperature as well as the variety of properties that emerge from the few known binary transition-metal–Pb compounds, this research focuses on accessing and...
This thesis is composed of two major parts. The first major part includes the first two chapters. In Chapter 1, we go over the history and background of spin glass theory and introduce the Sherrington-Kirkpatrick (SK) model and the Ghatak-Sherrington (GS) model. In Chapter 2, we introduce the Thouless-Anderson-Palmer (TAP)...
Two major areas of research in the field of manufacturing are miniaturization and 3D printing. The trend towards miniaturization stems from the desire and need for additional functionality and improved performance for products with ever-smaller footprints. Miniaturization opens manufacturing to new applications such as tissue engineering and surface texturing. Meanwhile,...
In the first chapter I introduce the ideas that link selling information to surplus extraction. In my environment the seller may be uncertain about how much the buyer both has already learned before contracting with the seller (belief types) and is able to learn after contracting with the seller (information...
Over the last decade, a rising trend of corporations publicly acting on social and political issues has come to the fore. The issues and methods have both varied widely—from immigration to abortion, and from advertisements to boycotts. This introduces an interesting puzzle in the realm of strategy research: Where does...
Heterogeneous catalysts based on metal oxides are of significant interest for many industrial chemical reactions. These catalysts, however, often suffer from ill-defined structures that preclude better understanding of the surface phenomena. Thus, structurally well-defined catalysts have received growing attention by making it feasible to understand the kinetics and reaction mechanisms....
Prenatal alcohol exposure is a global health concern. Despite guidelines advising against it, many women continue to drink throughout their pregnancies. Exposure to alcohol can have lifelong medical, social, emotional, and intellectual consequences on a developing fetus. Women in Uruguay have demonstrated consistently high self-reported alcohol consumption during pregnancy, but...
Computer systems supported by photonic interconnects and photonic memory devices can reach performance and energy efficiency levels unattainable through purely electronic means across scales, from processor chips to the data center. However, the promised benefits cannot be realized through a simple replacement process; to reach their full potential, several aspects...
This dissertation includes the score and companion essay to the musical work, Untitled (March). In the composition, I endeavor to create a listening situation offering a mutually negotiated environment of quietude that challenges a listener's preconceptions of intentionality and perception by blurring the boundaries between instrumental performance, field recordings, and the...
Social factors are a major contributor to deaths in the US. The literature suggests that socioeconomic status and other social and environmental factors influence an individual’s mortality. These factors encompass six domains that comprise factors such as poverty, unemployment, poor access to healthy food, limited access to health care, limited...
The three studies in this project investigate a selected number of youth protective factors and caregiver parenting skills with reducing the risk of justice involvement for youth involved in the child welfare system without a prior history of justice involvement. All three studies used child welfare administrative data, and the...
Built from non-covalent interactions, supramolecular biomaterials are highly dynamic and tunable, and recent work has shown that they are uniquely capable of mimicking functional biological structures. In this work, supramolecular biomaterials built from self-assembling peptide amphiphiles (PA) were investigated with the goal of precisely tuning their cohesive interactions to optimize...
Due to their widespread applicability, graphs and networks appear in various contexts. The increasing scale of graphs encountered in the real-world requires the developmentof efficient algorithms that run reasonably fast and produce close to optimal solutions.
The main focus of this thesis is the development of fast graph algorithms for...
Clientelism has been largely defined as an electoral strategy in which politicians distribute resources to voters to gather their support. This study proposes a new framework to understand clientelism by inverting the perspective of this practice, focusing on voters rather than politicians. This study proposes that clientelism should be understood...
If life exists on Mars, it likely resides in a deep subsurface environment. The Martian rocky subsurface is a primary target for the search for extraterrestrial life because it offers a stable habitat for microbial life. On Earth, the continental subsurface is a key astrobiological analog for understanding what properties...
Ataxic dysarthria is a disorder affecting the naturalness of speech due to damage to the cerebellum, a neural structure critical for the timing, scaling, and sequencing of speech movements (Ackermann, Vogel, Petersen, & Poremba, 1992; Diener & Dichgans, 1992; Duffy, 2013; Rampello, Rampello, Patti, & Zappia, 2016). In healthy individuals,...
Social media and online forums provide spaces where people can gather beyond restrictions of geographic proximity. For some individuals with mental illness, these spaces are vital; providing outlets and communities where a multitude of experiences are accepted and understood, rather than judged against normative, often ableist standards. For nearly three...
Maneuvering your limbs requires both accurate commands for how to move, and accurate feedback of their true movements. Conventional prosthetic arms currently lack this sense of proprioceptive feedback, which can make daily tasks difficult without close visual monitoring. Although studies have successfully provided artificial proprioceptive feedback to improve control, this...
Newborns are particularly susceptible to severe forms of herpes simplex virus type I (HSV-1) infection including encephalitis and multisystemic disseminated disease. The underlying age-dependent differences in the immune response that explain this increased susceptibility relative to the adult population remain largely understudied. Evidence from animal studies and genetic studies in...