Index Catalog // Arch : Northwestern University Institutional Repository

Start Over

Filtering by: Keyword Mitochondria Subject Medicine

1 - 2 of 2

List Gallery Masonry Slideshow

Novel Functions of Mitochondria-Lysosome Contact Sites in Health and Neurological Disease

Description:

Inter-organelle contact sites have become increasingly appreciated as important regulators of cellular homeostasis, and disruption of inter-organelle contact site dynamics and function has been observed in various pathologies. Recently, inter-organelle contact sites between mitochondria and lysosomes were discovered, offering a new mechanism by which these two organelles may directly interact,...

Keyword:

Imaging, Contact Sites, Lysosome, Mitochondria, Neurological Disease, and Calcium

Subject:

Biology, Medicine, and Neurosciences

Creator:

Peng, Wesley J

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

10/07/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15610 and etdadmin_upload_827420
Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species

Description:

Mitochondria-derived reactive oxygen species (mROS) are required for the survival, proliferation, and metastasis of cancer cells. The mechanism by which mitochondrial metabolism regulates mROS levels to support cancer cells is not fully understood. To address this, we conducted a metabolism-focused CRISPR/Cas9 genetic screen and uncovered that loss of genes encoding...

Keyword:

Reactive oxygen species, Cancer, Mitochondria, and Metabolism

Subject:

Biology, Health sciences, and Medicine

Creator:

Kong, Hyewon

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_775698 and http://dissertations.umi.com/northwestern:15362

LIBRARIES | ARCH

Limit your search

Type

Resource type

Creator

Keyword

Subject

Language

Novel Functions of Mitochondria-Lysosome Contact Sites in Health and Neurological Disease

Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species

Limit your search

Search Constraints

Search Results