The insulin/Insulin-Like Growth Factor (IGF) pathway is essential for linking nutritional status to growth and metabolism. MicroRNAs (miRNAs) are short RNAs that are players in the regulation of this process. The miRNA miR-7 shows highly conserved expression in insulin-producing cells across the animal kingdom. However, its conserved functions in regulation...
Periodic exposure to light and dark as a result of rotation of the Earth have served as a major evolutionary pressure to partition divergent biological processes to different phases of the day. Mammals display periods of activity/inactivity, wake/sleep, and feeding/fasting during distinct portions of the day. In mammals, these activities...
Skeletal muscle is one of the most abundant tissues in the body and makes up over 40% of the total body mass. It is important for mobility and posture maintenance as well as plays a central role in whole body metabolism. Skeletal muscle is made up of bundles of muscle...