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Designing Dynamic and Modular Biomolecules and Assays to Interrogate and Control Protein Fate

Description:

Cancer has long been the second-leading cause of death in the United States and represents the leading cause of death in midlife (age 40-60). While the prognosis for many cancers has vastly improved over the last thirty years, many cancers remain elusive due to the late-onset of symptoms, the specific...

Keyword:

Antibodies, Protein Switch, Cell Patterning, Machine Learning, and Breast Cancer

Subject:

Biomedical engineering

Creator:

Sykora, Daniel Joseph

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/16/2023

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_936187 and http://dissertations.umi.com/northwestern:16305
Mutational Processes Modeling and Early Cancer Diagnosis

Description:

Annual age-adjusted breast cancer incidence rates in the United States have been static for decades. More recently, the development of massively parallel, high throughput DNA sequencing has enabled the cataloging of somatic mutations in cancer. Mutations are non-random and occur within sequence motifs. These motifs provide us with evidence to...

Keyword:

Natural Language Processing, Electronic Health Records, Genomics, Mutational Processes, Breast Cancer, and Machine Learning

Subject:

Bioinformatics and Computer science

Creator:

Zeng, Zexian

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14500 and etdadmin_upload_635668

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Designing Dynamic and Modular Biomolecules and Assays to Interrogate and Control Protein Fate

Mutational Processes Modeling and Early Cancer Diagnosis

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