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Strategies to Model the Testis ex Vivo and in Vitro

Description:

The engineering of human reproduction is one of the defining scientific advances of the past century. Methods to specifically engineer the testis have an equally long and rich history, and have experienced significant progress over the past two decades, leading to current-day breakthroughs which are shifting the paradigms by which...

Keyword:

testis, model, organoid, reproduction, microenvironment, and explant

Subject:

Bioengineering, Biology, and Endocrinology

Creator:

Edmonds, Maxwell Ethan

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

01/21/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_743728 and http://dissertations.umi.com/northwestern:15119
Loss of Transcriptional Repression by Adipocyte BCL6 Results in Adiposity and Insulin Sensitivity

Description:

The epidemic of obesity and associated metabolic diseases have led to increased scrutiny of adipose tissue and its primary cell type, the adipocyte. However, studies show that regional adipose tissue distribution rather than obesity per se is a major determinant of metabolic disease risk. Despite having an obese body mass...

Keyword:

Lipogenesis, Insulin Sensitivity, Hypertrophy, Obesity, BCL6, and Adipocyte

Subject:

Biology, Endocrinology, and Genetics

Creator:

Senagolage, Madhavi Dushyanthi

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14575 and etdadmin_upload_658480

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Strategies to Model the Testis ex Vivo and in Vitro

Loss of Transcriptional Repression by Adipocyte BCL6 Results in Adiposity and Insulin Sensitivity

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