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- Description:
- Cobalt(III) Schiff-base complexes (Co(III)-sb) have been utilized in the literature as antibacterial, antiviral, and inhibitory agents. Recent work has utilized their ability to displace endogenous metals from metalloproteins that exhibit aberrant gain of function pathologies in human disease. Specifically, in this dissertation Co(III)-sb has been applied as inhibitors of pathogenic...
- Keyword:
- Transcription Factors, Coordination Complexes, Cobalt, Amyloid-beta, Molecular Dynamics, and Intrinsically Disordered Proteins
- Subject:
- Chemistry, Biochemistry, and Biophysics
- Creator:
- Brue, Christopher Robert
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15862 and etdadmin_upload_863221
-
- Description:
- Travel time is a key aspect of capturing and evaluating the operational performance and service quality of transportation systems, and travel time improvement is a common objective for travelers, service providers, transportation practitioners and agencies. However, the reliability of travel times, including the probability of unexpected delays, is an important...
- Keyword:
- algorithms, networks, travel time reliability, stochastic networks, routing, and path finding
- Subject:
- Transportation, Operations research, and Civil engineering
- Creator:
- Filipovska, Monika
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_850853 and http://dissertations.umi.com/northwestern:15794
-
- Description:
- At its core, the purpose of microscopy is to make objects and their underlying structures visible under high magnification. With the remarkable progress of electron microscopy, the sub-micron “high” magnification of light microscopy has been completely refashioned to encompass subatomic length scales. Unfortunately, higher-magnification does little to negate existing interpretability...
- Keyword:
- Image Similarity, Computer Vision, Atomic-Resolution Microscopy, Global Structure Optimization, Self-Annotated Datasets, and Information Extraction
- Subject:
- Materials Science, Computational physics, and Computer science
- Creator:
- Schwenker, Eric
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15860 and etdadmin_upload_862806
-
- Description:
- Plasmonic nanoparticles have very large absorption cross sections and can concentrate the local density of photon states on the nano scale. When they are coupled to molecules or semiconductor nanocrystals and form different hybrid nanostructures, various light-matter interaction processes can be significantly enhanced or manipulated, including optical responses like fluorescence...
- Keyword:
- plasmon, nanostructures, and surface-enhanced Raman spectroscopy
- Subject:
- Physical chemistry and Materials Science
- Creator:
- Wu, Yue
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15861 and etdadmin_upload_862992
-
- Description:
- As fourth-generation synchrotron x-ray sources start to come online, they bring with them the promise of increased imaging speed and resolution for current imaging modalities, while enabling entirely new ones. Employing the increased brightness at hard x-ray energies begins with having efficient focusing optics in place. Zone plates are popular...
- Subject:
- Physics and Computational physics
- Creator:
- Syed, Sajid Ali
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15831 and etdadmin_upload_857546
-
- Description:
- Recently, machine learning and deep learning, which have made many theoretical and empir- ical breakthroughs and is widely applied in various fields, attract a great number of researchers and practitioners. They have become one of the most popular research directions and plays a sig- nificant role in many fields, such...
- Keyword:
- Algorithm Design, Deep Learning, Optimization, and Machine Learning
- Subject:
- Applied mathematics and Operations research
- Creator:
- Fang, Biyi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15817 and etdadmin_upload_855647
-
- Description:
- Fluctuations are ubiquitous in physics.For a system close to a phase transition, the order parameter fluctuations are strong. In this thesis we study the pair fluctuations in liquid 3He when it is close to the superfluid phase transition. Liquid 3He is a neutral Fermi liquid, which allows zero sound to...
- Keyword:
- pair fluctuations, liquid 3He, and zero sound
- Subject:
- Condensed matter physics
- Creator:
- Lin, Wei-Ting
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_863491 and http://dissertations.umi.com/northwestern:15872
-
- Description:
- The purpose of my thesis research has been to understand the formation of mitotic chromosome structure by using chromosome micromanipulation. Folding mitotic chromosomes from their loose interphase form into their individualized, compacted form is required for easy handling of the chromosomes for cell division. This process is facilitated by several...
- Keyword:
- Mitosis, Histone PTMs, Chromosomes, SMC Complexes, Biophysics, and Meiosis
- Subject:
- Molecular biology and Biophysics
- Creator:
- Biggs, Ronald Joseph
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15852 and etdadmin_upload_862016
-
- Description:
- This dissertation describes three studies which develop a deeper understanding of both failure and performance in human service referral networks focusing on veterans. It draws on theories across network science, public administration, organizational communication, and technology design to explore three major questions: 1) how stakeholders in veteran care networks define...
- Keyword:
- referral network, network effectiveness, network failure, veteran care, network performance, and service network
- Subject:
- Management, Organization theory, and Communication
- Creator:
- Gibson, Zachary Michael
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_863338 and http://dissertations.umi.com/northwestern:15866
-
- Description:
- In the past decade, the e-hail service provided by transportation network companies (TNCs) gained popularity in major cities around the world. By allowing passengers to virtually “hail” vehicles on mobile phones, e-hail has revolutionized the matching process in ride-hail, drastically reducing the existing search friction. However, previous studies found the...
- Subject:
- Transportation
- Creator:
- Zhang, Kenan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15842 and etdadmin_upload_859795