Levels of the several different human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) cytidine deaminases vary across different cell types. While levels of nuclear-localized A3s are low or non-existent in primary cells, a nuclear A3 is often upregulated in cancer cells. Increased chromosomal mutagenesis due to nuclear A3...
Two-dimensional (2D) covalent organic frameworks (COFs) are a class of crystalline polymer networks that polymerize and crystallize into layered structures, characterized by their atomically precise structure, permanent porosity and high modularity. Imine-linked COFs are one of the most important and promising classes of macromolecular sheets, which form by the condensation...
Stroke affects millions of people each year and although modern medicine has improved chances of survival after stroke, it has not yet been able to affect a change in repairing damaged neural tissue leaving one to two-thirds of survivors with chronic disability in their affected upper-extremity; specifically, hemiparesis, hypertonicity, loss...
This dissertation examines caregiving contexts in early childhood. Specifically, I look at how caregiving contexts are related to or influenced by other caregiving contexts and broader social contexts. The dissertation is composed of an introductory chapter that provides a theoretical overview and summary of the dissertation followed by two additional...
Increasingly high global energy consumption demands effective approaches to high energy efficiency and, at the same time, paths to reduced release of carbon dioxide, a primary greenhouse gas behind global climate change. Friction reduction is a vital aspect towards making energy systems more efficient and one of the most crucial...
This dissertation explores how items encountered in the comprehension of language are stored in memory and subsequently accessed. Processing and comprehending language frequently requires the retrieval of items in memory so that a current linguistic element can be assigned an interpretation. For example, in a sentence such as "Miles loved...
Gold nanoparticles (AuNPs) display unique characteristics compared to their macro-counterparts that are dependent on shape, size, and attached surface molecules. Methods have been developed to precisely control both size and shape of AuNPs for specific applications. The biocompatibility, plasmonic properties, and ease of functionalization with thiolated molecules, make gold nanoparticles...
This dissertation provides evidence that reading is best explained as rational gathering of visual information to identify words efficiently. Although empirical evidence from human reading research suggests a close link between eye movements and cognitive process, it is not clear how readers decide when and where to move their eyes...
AbstractThis dissertation consists of three papers examining economic issues in developing countries.
The first paper studies how export activity affects prices in domestic consumer markets. Using extensive, spatially disaggregated data from India’s rice markets and exploiting a natural experiment provided by India’s rice export restrictions during 2007-2011, I show that,...
Active lateral force feedback is essential for haptic applications in which forces on the fingertip is perpendicular to or in the same direction of finger movement, such as virtual shape rendering and button click rendering. In this thesis, I first present a novel device, the UltraShiver, that can provide large...