Transnational adoption from Asia to the U.S. was institutionalized in the 1950s, when the Korean War left an estimated 100,000 Korean children orphaned or displaced. At the time, the practice was situated as a form of emergency rescue, an act of win-win humanitarianism in which average Americans could take part...
Transcription plays a pivotal role in the transfer of genetic information within living organisms. It serves as the initial step in gene expression, allowing cells to convert the instructions encoded in their DNA into functional molecules. Eukaryotic transcription initiation is a complex and dynamic process that requires joint efforts from...
Gastrointestinal (GI) colonization by Klebsiella pneumoniae is a risk factor for subsequent infection as well as transmission to other patients. Additionally, colonization is achieved by many strain types that exhibit high diversity in genetic content. However, how K. pneumoniae achieves colonization and whether the genetic factors it uses differ by...
Mission-critical systems are those imperative systems whose failures can result in catastrophic consequences. Traditional techniques, such as manual investigation and testing, cannot ensure the absence of errors and security vulnerabilities within these systems. This dissertation leverages formal methods to comprehensively examine several mission-critical systems and their essential components. For each...
The advent of advanced computing and AI has led to social technologies becoming agentic teammates in human-autonomy teams. Interpersonal trust, vital for team functioning, is crucial in determining these teams' success or failure. Trust, while essential, can be easily broken and requires maintenance and repair. This dissertation addresses two questions:...
Breast cancer patients have reported nonspecific neurologic symptoms such as fatigue, depression, and cognitive concerns while undergoing adjuvant therapy. Few neuroimaging studies have examined hormone therapy, an adjuvant therapy, and more research is needed to determine possible neurologic and cognitive effects. Previous estrogen research has found alterations in gray matter...
This dissertation uses the case of Colombia to examine the causes and reproductive mechanisms of civil wars that last more than fifty years, which I call perpetual civil wars. It draws on network analysis of violent events and political claims, content analysis of official archival documents and historical records of...
Swallowing impairment or dysphagia has many possible causes with severe sequelae. One major mediator of the relationship between causes and sequelae is the physiologic impairment of the swallowing mechanism. Assessing the physiology of swallowing impairment is of great importance so that treatment can target physiology to mitigate sequelae. The assessment...
The political history of late twentieth-century Southern Africa was dominated by violent liberation struggles against settler-colonial domination in Angola, Mozambique, Namibia, South Africa, and Zimbabwe. All five countries experienced prolonged settler colonialism, followed by conflicts in which revolutionary national liberation movements (NLMs) sought to both end settler-colonial domination and build...
Recent experiments in participatory democracy, such as Iceland’s 2013 Constitutional Reform process to Chicago’s annual participatory budgeting process, have empowered members of the public to directly make policy decisions. These new participatory democratic institutions depend on citizens having capacity to organize new institutions and the capacity to participate in them....
Derivative-free optimization (DFO) has received growing attention due to important problems arising in practice. Various research communities, ranging from machine learning to engineering design, have adopted distinct DFO methods. In this thesis, we present extensive studies as a meaningful step towards a comprehensive understanding of DFO methods. We study the...
In this work, I try to understand how the movements, attitudes, styles, and positions of the body in representational artworks can be understood as gestures—that is, as moments that interrupt the unfolding of narrative time and produce an interval. The interval is not merely a space that opens up between...
This dissertation theorizes the relation between blackface minstrelsy and contemporary Black performance. The project analyzes the use of nineteenth-century blackface minstrel conventions in Black theatrical performances during later eras where its usage seems counter-intuitive: during the Black freedom struggles of the 1960s; within Black feminist and queer performance of the...
In recent years, the understanding and identification of quantum materials supporting non-trivial band topology has progressed rapidly. This progress has been motivated in part by the potential application of topological quantum materials in quantum computers, sensors, and other next-generation devices. Despite this progress, the computation of bulk topological invariants in...
This dissertation focuses on quantifying protein folding stability determinants and presenting initial experiments that can guide the development of a novel assay that identifies cell-penetrating miniproteins. First, despite over a century of scholarship on protein folding stability, applying this knowledge to design proteins computationally remains limited. Usually, protein designers generate...
This project explores how the variation in language experiences and attitudes that Mexican American Spanish heritage speaker bilinguals in the United States have affects their speech perception in both their languages. Heritage language bilinguals speak as a first language a minority language that they have cultural ties to (e.g., Spanish...
This dissertation investigates how scope relations are constructed and evaluated during real-time human sentence processing. Theoretical approaches to processing scope relations exist in a multi-dimensional space where trade-offs are made around how quickly scope relations can be computed, how many mistakes are made in computing scope relations, and how many...
The field of distributed optimization algorithms is wide and growing, and new techniques for categorizing and analyzing existing algorithms are continually being developed. In this Thesis, we leverage control theoretic analysis and block diagram interpretations for existing algorithms to synthesize entirely new families of algorithms. These new algorithm families have...
Transitioning energy systems from a reliance on fossil fuels to low carbon energy sources is an essential solution for climate change mitigation. However, the industrial sector, which is directly responsible for more than a quarter of global carbon dioxide (CO2) emissions, continues to use fossil fuels for energy and feedstocks....
Necessity is the mother of innovation. In the wake of the pandemic, with no flow of samples and limited fabrication techniques available, necessity demanded a new material platform and adaptable methods to make complex oxide samples worth measuring. The material platform was KTaO3 , the younger successor to the mainstay...