Cancer is a top leading cause of deaths worldwide, among which pancreatic cancer and liver cancer are top leading cause of cancer-related deaths. Despite recent developments in cancer treatment, pancreatic and liver cancers still have a high mortality and low life expectancy, especially when diagnosed at advanced stages. Earlier cancer...
This dissertation explores the reciprocal relationship between international politics and digital computation since the 1960s by examining the first attempts to use computer simulation to credibly forecast our planet’s economic and environmental future on a global scale. In particular, this project offers the first sustained historical analysis of the origins...
This dissertation investigates how US Americans in the nineteenth century began to apply the category of religious fanaticism to individuals and communities deemed dangerous. Contributing to scholarship on secularism, racial governance, and American religious history, this dissertation argues that fanaticism is not a neutral category of description. It tracks how...
A core problem in many computer vision applications is visual recognition (including object classification, detection and localization). Recent advances in artificial neural networks (aka ”deep learning”) have significantly pushed forward the state-of-the-art visual recognition performances. However, due to the lack of semantic structure modeling, most current deep learning approaches do...
The fact that informational asymmetries impose a significant barrier in path of smooth functioning of markets has been well known in Economics since the 1970s. Communication and information exchange allow to mitigate these barriers to a certain extent. The existing Economic literature allows to get a good grasp of static...
The unique ability of plasmonic nanoparticles to localize and enhance resonant electromagnetic fields has enabled a wealth of discoveries from enhanced spectroscopies to driving chemical reactions on the nanoscale. In this thesis, we strive to both drive and observe chemistry on plasmonic surfaces. First, we examine the possibility of driving...
Nature and Civilization is a focused interpretation of Kant’s politics insofar as it bears on the distinction between nature and civilization. It seeks to answer the question, How is Kant’s distinction between nature and civilization informing his global political thought? Kant thinks that in moving from the state of nature...
The prospect of being evaluated by others is oftentimes psychologically crippling. At the core of feeling evaluated is perceiving other minds capable of possessing (judgmental) thoughts and feelings. While research on mind perception in evaluative situations oftentimes examines positive aspects (e.g., increased prosocial behavior), this dissertation looks into how mind...
This dissertation studies three aspects of healthcare market regulation.
Chapter 1 studies the optimal design of quality scores for health insurance plans. Regulators often generate quality scores to help consumers with limited information about product quality, as in schooling, healthcare, and financial markets. When designing scores, regulators must not only...
In the nineteenth century, Jews across Europe entered a period of emancipation, at best a vaguely defined term that indicated the granting of equal civil and political rights, though sometimes conditionally and often incrementally. Concurrent to this, art music was dominated by deep divisions of stylistic and aesthetic approaches to...
The Operating System (OS) kernel is a key component of modern computing infrastructure, yet it is prone to numerous vulnerabilities, many of which cause memory corruptions that can be exploited by attackers to perform malicious activities. While various techniques have been introduced to secure the Linux kernel, it still constantly...
This dissertation examines the legal, economic, and social transformations experienced by American widowed women from the Salem Witchcraft Trials to the Civil War to expand how scholars of literature, the law, and American history define women’s citizenship prior to suffrage. Emphasizing literature’s importance to nineteenth-century nation-building during the era of...
We study plurisubharmonic functions and their applications to K\"ahler geometry. We begin by studying regularity of envelopes of plurisubharmonic functions, particularly when the reference form is degenerate. This is then applied to show regularity of geodesic of K\"ahler metrics on singular varieties, as well as regularity of certain geodesic rays....
This dissertation examines how one pervasive state institution¬—schools—shapes the political behavior of young people along the lines of race and ethnicity. I make four primary claims. First, I show that the content of traditional civic education courses privileges the political experiences of white political actors. Second, I argue that this...
The task of classification has been increasingly attracting attention from researchers in recent years. The objective is to assign labels given attributes of samples. The classification task is practical in real-world applications and is widely explored in fields such as computer vision, natural language processing and information retrieval. The recent...
With the ever-increasing demand for more complex functionalities and miniaturization of photonic devices, the design of such devices requires a whole new different approach, deviating from classical photonic design approaches. Conventionally, the design of a typical photonic device starts with a prior knowledge, intuition, and practical experience of specific behavior...
Use of bio-renewable polysaccharides to produce materials with a high technological impact has gained a lot of attention recently. Efforts have been made, for example to produce triboelectric generators from cotton, as well as, nanostructures of chitosan gels for drug delivery. Another well-known example is the use of β-Cyclodextrin (β...
This dissertation investigates a number of models and algorithms in the context of optimization under uncertainty. The focus is on risk-averse optimization, where risk aversion is modeled via stochastic dominance, utility theory, and distributionally robust optimization. We first investigate an investment model with fixed contribution rates, optimize asset-allocation decisions in...
In the first two decades of the twenty-first century, we have witnessed a surge of public interest in and discussion around racial reckoning. Universities in the United States and across the globe are grappling with their historical associations with transatlantic and chattel slavery. This dissertation takes up the question of...
The three dimensional structure of a protein determines its biological function. How a protein folds, however, has been the central research problem for decades. The intermediates on the folding paths, which the protein can assume transiently, are of particular interest as they not only reveal the structural dynamics of a...