One of the main drivers of complexity in a service system is the dependence between different random variables describing the system. For example, the queue lengths at different time points and the waiting times of different items (jobs, customers) in queue are strongly dependent. To reduce dependence-related complexities, it is...
Patterning hierarchical structures in three-dimension (3D) has created nature-inspired functional surfaces. Gecko feet structures have been mimicked for reversible adhesive properties, shark skin for reduced drag, and lotus leaves for self-cleaning surfaces. Rational design of out-of-plane patterns across multiple length scales is crucial because each micro- and nano-feature has different...
My dissertation consists of two chapters that empirically study policy-related questions in applied microeconomics by using structural econometric modeling developed in industrial organization. In the first chapter, I study the welfare effects of a cap-and-trade program. I develop an equilibrium framework that incorporates forward-looking behavior and transaction costs. In the...
The ability to efficiently sense and respond to molecular signals is crucial for any organism's survival. Sensitive, specific and timely, microbial sensing systems provide an excellent starting point for the engineering of single-celled organisms to detect new molecules of human interest. Towards this goal, our lab pursues the engineering of...
The objective of this work has been the design of new lubricant additives to target friction in the boundary lubrication regime and the hydrodynamic lubrication regime. Modern automotive engines operate at higher temperatures and speeds than ever before, and therefore require new and more effective lubricant additives to meet higher...
The mammalian retina harbors more than 30 output channels, each playing a distinct role in processing visual images. A comprehensive understanding of the retinal code primarily relies on the functional knowledge of individual output neurons or retinal ganglion cells (RGCs). Despite recent technical advances in imaging and genetics, the function...
Chapter 1: Product Market Strategy and Capital Structure: Evidence from Resale Price Maintenance', "This paper studies how a firm's pricing strategy affects its financial leverage. Retailers vary in pricing strategy, ranging from low markup (i.e., ``discount''), no frills retailers to high markup retailers that offer extensive service. The choice of...
Spherical nucleic acids (SNAs) are a class of structures composed of spherical nanoparticle cores that are densely functionalized with radially oriented, linear DNA. SNAs exhibit properties that are distinct from those of their linear counterparts. These constructs can readily enter cells, evade nuclease degradation, and bind complementary DNA targets with...
Self-assembled monolayers as tunable chemical platforms broadly enable the study of the interaction between biological species and synthetic surfaces. Unlike small molecule chemistry where the freely diffusible product can interact with biological targets as an inhibitor or probe, interfacial chemistry allows for the controlled and multi-valent presentation of ligands to...
Research on rat whiskers offers knowledge in neuroscience analogous to humans\' sense of touch and inspiration for efficient sensing robotics. The present work investigates the rat whisker system from a mechanical engineering perspective. First, key quasi-static and dynamic properties were quantified in Chapter 2 for individual whiskers in an array,...