The answer to the question “Why do we sleep?” lies in understanding the biological underpinnings of homeostatic drive to sleep. Wakefulness is correlated with numerous changes in brain activity, structure and gene/protein expression that re-normalize following sleep however which of these elements is sufficient to cause sleep drive and how...
Nearly all animals exhibit behaviors that can be classified as sleep. The distinctly disadvantageous nature of the asleep state, evolutionarily speaking, accentuates its role as a critical physiological process, yet chronic inadequate sleep is prevalent in today’s society. Among the multitude of health problems that have been linked to chronic...
Slow-wave sleep (SWS) is important for overall health since it affects many physiological pathways from cardio-metabolic health to cognitive function. Sleep and autonomic nervous system (ANS) functioning are closely coupled at anatomical and physiological levels. Sleep-related changes in ANS function are likely the main pathway through which SWS affects many...
Rhythmic fluctuations of electrical activity in the brain provide insights into the proposed mechanism by which we encode experiences and then maintain, forget, modify, and retrieve them. Yet there is still much to learn about how neural oscillations relate to memory function. The purpose of this research is to discover...