The physical boundary layer, or interface, between two different phases of matter is the site of chemical and physical processes that are critical to many research fields. Many of these interfaces contain electric charge, which influences the structure and composition of the interfacial region and the interactions between the interface...
Supported vanadium oxide materials have been extensively studied for alkane oxidative dehydrogenation (ODH) reactions due to their high activity and selectivity. The catalytic activity of supported VOx materials is influenced by the surface coverage of VOx sites and hence the distribution of V=O, V-O-V, and V-O-S (S, support) bonds. The...
The role of nuclei nanoenvironment in cellular function has been a challenging problem in biology due to the lack of chromatin 3-dimension (3D) structure imaging/capturing techniques and theory connecting physical structure of chromatin to transcription. Recent studies on optical properties measurement on biological sample techniques, nanoscale imaging techniques and chromatin...
Gene regulatory networks (GRNs) are important abstractions of the complex regulatory interplays between genes, proteins, metabolites, and other molecular-level entities. Comprehensive GRNs provide high-level overviews of the topology of gene-gene interactions and their purposes, thereby enabling a comprehensive understanding of their role in phenotypic variation, disease mechanisms, and other biological...
This dissertation examines the language of force in Robert Musil’s Der Mann ohne Eigenschaften (MoE) as a site of literary self-reflection. It investigates how the text employs a constellation of “force” terms – including not only the words Kraft, Energie, and Leistung, but also images of physical and chemical forces...
In this thesis we present methods for estimating network metrics via random walk sampling. More specifically, we generalize the Hansen-Hurwitz estimator and the Horvitz-Thompson estimator to estimate the shortest path length distribution (SPLD), closeness centrality ranking, and clustering coefficients of a network. Those are important metrics to a network, but...
Circuit-level Dynamic Timing Slack (DTS) has emerged as a compelling opportunity for eliminating inefficiency in modern low-power systems. This slack arises when all the signals have propagated through logic paths well in advance of the clock signal. When it is properly identified, the system can exploit this unused cycle time...
This dissertation is about three of Cicero’s notable projects in ideal theory in his middle and late periods (between roughly 54-43 BCE). It comes during a resurgence in interest in Cicero’s contributions as a philosopher. First, I discuss Cicero’s philosophical account of vera gloria (true glory) in contradistinction to mere...
This dissertation proposes an oracle efficient estimator in the context of a sparse linear model. Chapter 1 introduces the penalty and the estimator that optimizes a penalized least squares objective. Unlike existing methods, the penalty is differentiable – once, and hence the estimator does not engage in model selection. This...
Rationally assembled nanostructures exhibit distinct physical and chemical properties beyond their individual units. The development of nanofabrication tools enables precise structural defining of nanomaterials scalable to large areas. This dissertation focuses on plasmonic nanoparticle arrays that show unique diffractive coupling with lattice spacings engineered close to the wavelength of light....