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Filtering by: Keyword nucleocytoplasmic transport Subject Cellular biology Subject Molecular biology Subject Neurosciences

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Description:: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by motor neuron (MN) degeneration and resulting in progressive paralysis and death. ALS is genetically heterogeneous, disease pathophysiology is not completely understood, and there are no effective drug therapies. To develop broadly applicable therapeutics, we examine disease mechanisms in the...
Keyword:: ALS, C9orf72, iPSCs, nucleocytoplasmic transport, NEK1, and microtubules
Subject:: Molecular biology, Cellular biology, and Neurosciences
Creator:: Daley, Elizabeth
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 10/07/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15607 and etdadmin_upload_825395

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