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- Description:
- Abstract Kaposi sarcoma (KS) is the most common cancer associated with human immunodeficiency virus/ Acquired Immunodeficiency Syndrome (HIV/AIDS) infection worldwide and it is the most prevalent cancer in some countries in sub-Saharan Africa (SSA). The introduction of combination antiretroviral therapy (ART), led to dramatic declines in KS morbidity and mortality,...
- Keyword:
- HIV, Kaposi Sarcoma, opportunistic infections, antiretroviral therapy, Nigeria, and sub-Saharan Africa
- Subject:
- Health sciences
- Creator:
- Akanbi, Maxwell Oluwole
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_742578 and http://dissertations.umi.com/northwestern:15096
-
- Description:
- This dissertation contains four essays. The first essay, Strategically Giving Service: The Effect of Real-Time Information on Service Efficiency, analyzes the impact of the increased availability of real-time information on the behavior of strategic agents and the implications of this phenomenon for service efficiency using data from one of the...
- Keyword:
- service operations, operations management, and empirical operations
- Subject:
- Business administration
- Creator:
- KARACAOGLU Garro Beraza, Nil
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14611 and etdadmin_upload_661699
-
- Description:
- Localized corrosion involves the selective attack of a metal at a small, exposed site. This can be particularly devastating for load-bearing structures like bridges, which can fail catastrophically even with very little material loss. Unfortunately, such corrosion is very hard to prevent, predict, and detect. Corrosion can be prevented by...
- Keyword:
- liquids, coatings, and self-healing
- Subject:
- Materials Science
- Creator:
- Lim, Alane Tarianna Ocampo
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_663032 and http://dissertations.umi.com/northwestern:14674
-
- Description:
- Records of temperature and precipitation during Quaternary interglacial periods on Greenland are notably scarce, limiting assessment of the magnitude and rate of local environmental response to orbitally-driven Arctic warming. It is largely unknown if warming across Greenland was spatially uniform through past interglacials, and if warming was accompanied by major...
- Keyword:
- Chironomid, n-alkanes, n-acids, Greenland, Hydrogen isotopes, and Paleoclimate
- Subject:
- Paleoclimate science
- Creator:
- McFarlin, Jamie Marie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_661785 and http://dissertations.umi.com/northwestern:14613
-
- Description:
- Solid acid fuel cells confer unique advantages over nearby technologies, such as polymer electrolyte membrane fuel cells (PEMFCs) or solid oxide fuel cells (SOFCs), due to the solid acid electrolyte – a solid-state, anhydrous, intermediate-temperature proton conductor.Despite these encouraging unique properties, solid acid fuel cells have performed unfavorably in comparison...
- Keyword:
- Solid Acid Fuel Cells, proton conductor, CsH2PO4, Superprotonic, Solid Acid Electrolytes, and CDP
- Subject:
- Materials Science and Energy
- Creator:
- Wang, Louis Shen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_971560 and http://dissertations.umi.com/northwestern:16452
-
- Description:
- In solar energy conversion ranging from artificial photosynthesis to photocatalysis, transition metal complexes (TMC) are essential building blocks due to several attractive properties: intense absorption within the solar spectrum, presence of charge-transfer excited state, and substrate binding capability through coordination geometry changes. In order to gain insight into controlling solar...
- Keyword:
- Transition Metal Complex, Excited state dynamics, and X-ray Transient Absorption Spectroscopy
- Subject:
- Physical chemistry
- Creator:
- Hong, Jiyun
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_662106 and http://dissertations.umi.com/northwestern:14629
-
- Description:
- In this thesis, I explore the formation and evolution of neutron stars and millisecondpulsar populations in globular clusters using N-body simulations. In particular, I examine how the number of millisecond pulsars and the pulsar properties, including binary properties and different pulsar types, depend on the dynamical cluster environment. I demonstrate...
- Keyword:
- STAR CLUSTERS, N-BODY SIMULATIONS, PULSARS, NEUTRON STARS, and COMPACT OBJECTS
- Subject:
- Astronomy and Astrophysics
- Creator:
- Ye, Claire Shi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_932107 and http://dissertations.umi.com/northwestern:16285
-
- Description:
- Movement and sensing fundamentally works in a synergistic manner. Animal's sensory organs --- be they independently movable like eyes or requiring whole body movement as in the case of electroreceptors --- are actively manipulated throughout stimulus-driven active sensing behaviors. Though these sensing-related motions have been individually reported and analyzed across...
- Keyword:
- behavior, uncertainty, Shannon-Weaver entropy, exploration-exploitation tradeoff, active sensing, and information theory
- Subject:
- Artificial intelligence, Neurosciences, and Engineering
- Creator:
- Chen, Chen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_675222 and http://dissertations.umi.com/northwestern:14742
-
- Description:
- Recent development on optogenetic methods offers reliable path to modulate cell activities with high level spatiotemporal precision. Application of this technology in behavior studies significantly improves our understanding in the neural principle that underpin animal behaviors, including ourselves. Full exploitation of optogenetic method in neuroscience behavior studies relies on...
- Keyword:
- Wireless, Neuroscience, Optogenetics, Robotics, and Battery-free
- Subject:
- Engineering
- Creator:
- Yang, Yiyuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_815460 and http://dissertations.umi.com/northwestern:15529
-
- Description:
- Situated at the intersection of literary, religious, and economic studies, this dissertation examines how late medieval writers used commercial practice to invent new modes of penitential piety. Challenging scholarship that characterizes the relationship between church and commerce as exclusively antagonistic or corrosive, I argue that the convergence of these two...
- Keyword:
- economic humanities, penance, religious practice, lay piety, and commerce
- Subject:
- English literature
- Creator:
- Jiang, Nancy Haijing
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_962361 and http://dissertations.umi.com/northwestern:16416
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(Being a) Feminist (is a) Struggle: Intersectional Feminist Politics in the Era of The Women’s March
- Description:
- “(Being a) Feminist (is a) Struggle: Intersectional Feminist Politics in the Era of the Women’s March” argues that contemporary feminist politics are characterized by debates and contestations concerning the political demands of intersectionality. Contemporary feminist theory and politics are particularly and peculiarly preoccupied with making these judgements about the political...
- Keyword:
- Intersectionality, Feminist Theory, Feminism, and Political Theory
- Subject:
- Political science
- Creator:
- Auriemma, Rhiannon L
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16068 and etdadmin_upload_902338
-
- Description:
- Proteins represent a critical class of biomolecules, universally employed by all living organisms to fulfill essential structural, functional, and enzymatic roles necessary to support life. In nature, these polymers are composed generally of twenty natural amino acid (AA) building blocks, which can be modified with covalent adducts known as post-translational...
- Keyword:
- post-translational modification, genome engineering, cell-free protein synthesis, synthetic biology, orthogonal translation system, and non-canonical amino acid
- Subject:
- Bioengineering, Biology, and Biochemistry
- Creator:
- Des Soye, Benjamin James
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14473 and etdadmin_upload_627384
-
- Description:
- Methanotrophs, bacteria that can metabolize methane, remain a promising solution to mitigating the effects of climate change by removing atmospheric methane and converting it to useful chemical precursors. However, a full understanding of the main enzyme they use to oxidize methane, particulate methane monooxygenase (pMMO), is critical for harnessing their...
- Keyword:
- cryogenic electron tomography, particulate methane monooxygenase, membrane protein, cryogenic electron microscopy, and cell-free protein synthesis
- Subject:
- Molecular biology, Biochemistry, and Biophysics
- Creator:
- Koo, Christopher Wellington
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_897671 and http://dissertations.umi.com/northwestern:16003
-
- Description:
- Despite prevention and treatment, substantial risk for cardiovascular disease(CVD) remains in the population and CVD has been the leading global cause-of-death in past years.While high-density lipoprotein (HDL) markers such as HDL cholesterol (HDL-C) and HDL efflux (a cholesterol-transport-function assay) are associated with decreased risk of CVD, the mechanism of this...
- Keyword:
- Cardiovascular Disease, Apolipoproteins, Post-translational Modifications, Proteoforms, and Top-down Proteomics
- Subject:
- Chemistry
- Creator:
- dos Santos Seckler, Henrique
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_791345 and http://dissertations.umi.com/northwestern:15443
-
- Description:
- This dissertation imagines the near future of teamwork, when AI agents will join teams,interacting, collaborating, and completing tasks as a team member. Broadly, I seek to answer the questions: how do humans integrate a new AI teammate onto their team, and how does the AI teammate’s function influence this integration...
- Keyword:
- team, AI teammate, team technology adaptation, and team cognition
- Subject:
- Organizational behavior and Communication
- Creator:
- Larson, Lindsay Elizabeth
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15725 and etdadmin_upload_843833
-
- Description:
- This dissertation present a Compound Poisson Mixture Regression model of the distribution of transaction frequency and monetary value, and apply it to study donations at a private university in the Midwestern United States. The model captures the joint effect of covariates, recognizing that both response variables emanate from one statistical...
- Subject:
- Marketing and Transportation
- Creator:
- Bao, JIngyuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_810588 and http://dissertations.umi.com/northwestern:15511
-
- Description:
- Many estimation and inference procedures rely on asymptotic approximations for quantities that are unknown to researchers. While often convenient, such approximations can be poor in practice, even when the number of observations is ostensibly large. One response is to eschew asymptotics in favor of finite sample bounds. While remarkable progress...
- Subject:
- Economics
- Creator:
- Cai, Yong
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_986619 and http://dissertations.umi.com/northwestern:16598
-
- Description:
- This dissertation researches the Cenomanian, Turonian, and Coniacian Stages (100.5 - 86.3 Ma) of the Cretaceous Period, a geologic interval of interest due to its extreme global warmth, iconic faunas, and oceanic anoxic events (OAEs). Five globally dispersed geochemical and stratigraphic case studies reconstruct interactions of the mid-Cretaceous carbon cycle...
- Keyword:
- Stratigraphy, Isotope Geochemistry, Sea Level, Greenhouse Climate, Ocean Anoxic Events, and Cretaceous
- Subject:
- Geochemistry, Geology, and Sedimentary geology
- Creator:
- Jones, Matthew Madden
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14461 and etdadmin_upload_626920
-
- Description:
- This dissertation examines the following puzzle: Why have antitrust (competition) laws and policies failed in their mission to prevent concentrations of economic power globally? Corporate monopolization has grown more acute in the last three decades and created serious problems in consumer and worker protection, economic stability, and democratic representation worldwide....
- Keyword:
- Antitrust (competition) laws, Turkey, Economic sociology, Mexico, International political economy, and USA
- Subject:
- Sociology
- Creator:
- Arslan, Melike
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15662 and etdadmin_upload_836066
-
- Description:
- This dissertation contains two chapters. The first one is on microenterprises in developing countries and how they face competition from large corporations. The second one is on estimating the causal effect of childcare availability on the formation and persistence of gender gaps in the Mexican labor market. The first chapter...
- Subject:
- Economics
- Creator:
- Talamas Marcos, Miguel Angel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_898300 and http://dissertations.umi.com/northwestern:16012
-
- Description:
- How do ever-changing international systems and rapidly emerging technology shape counter-systemic revolutionary insurgent (CSRI) behavior and outcomes? The purpose of this publication is to identify causes and develop a conceptual typology of CSRI survival and behavior in a Post-9/11 era. I argue three global shocks acted as junctures for new...
- Keyword:
- Systemic and Insurgents
- Subject:
- International relations and Political science
- Creator:
- Humpal, Jesse
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15550 and etdadmin_upload_817723
-
- Description:
- This dissertation explores the relationship between cultural production in Puerto Rico from 2005 to the present and the unfolding debt crisis on the island. I explore the relationship between colonialism as an institution, coloniality as a broader structuring of power, and the current debt crisis by examining cultural objects that...
- Keyword:
- debt, decolonial, popular culture, Puerto Rico, and literature
- Subject:
- Latin American literature
- Creator:
- Rivera Montes, Zorimar
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_879798 and http://dissertations.umi.com/northwestern:15945
-
- Description:
- Affect represents a major domain of human consciousness, consisting of a complex group of psychophysiological processes to drive human behavior. Many genetic and environmental factors may cause dysregulation of affective states, resulting in disorders that severely disrupt normal cognitive function and diminish the quality of life. Transitions among affective states...
- Keyword:
- Dopamine, Optogenetics, and Affective disorders
- Subject:
- Neurosciences
- Creator:
- Wu, Mingzheng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_925290 and http://dissertations.umi.com/northwestern:16201
-
- Description:
- Organic semiconductors have shown great promise for optoelectronic applications, particularly solar photovoltaics. Critical to their success is the ability to understand and manipulate the relationship between molecular structure and bulk properties. Substantial progress on understanding structural influences on electronic properties has been made for the conjugated polymers and small molecules...
- Keyword:
- Aggregation, Ultrafast Spectroscopy, PTB7, Spectroscopy, Organic Semiconductor, and Organic Photovoltaic
- Subject:
- Physical chemistry, Chemistry, and Condensed matter physics
- Creator:
- Fauvell, Thomas James
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14521 and etdadmin_upload_639550
-
- Description:
- We present two novel, computational models of biofilm growth within an experimental flow cell. First, we use asymptotic approximations to develop a reduced model that captures the large-scale dynamics within an entire flow cell. The reduced model's predicted growth and nutrient distribution are close to the values predicted by previous...
- Subject:
- Applied mathematics
- Creator:
- Ford, Noah
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_764364 and http://dissertations.umi.com/northwestern:15266
-
- Description:
- In the face of a changing climate caused by anthropomorphic release of carbon dioxide and other greenhouse gases, major governments have committed to the reduction of CO2 and other emissions over time, requiring increased reliance on forms of carbon-free renewable energy. The inherent intermittency of renewable electricity sources creates a...
- Keyword:
- additive manufacturing, Solid oxide electrolyzer, Solid oxide fuel cell, ceramics, exsolution , and 3D-printing
- Subject:
- Nanoscience, Materials Science, and Engineering
- Creator:
- Geisendorfer, Nicholas R
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_873708 and http://dissertations.umi.com/northwestern:15899
-
- Description:
- The rise in children’s media use (Rideout & Robb, 2020) and the prioritization of STEM learning (Fayer et al., 2017) has led to the development of new STEM-related apps, TV shows, and other media for young children. One topic in this area gaining popularity is computational thinking (CT). Researchers refer...
- Keyword:
- Diversity, Culture and Inclusion, Computational Thinking, Early Childhood, Educational Television, and STEM
- Subject:
- Developmental psychology, Science education, and Communication
- Creator:
- Lemley, Breniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1011152 and http://dissertations.umi.com/northwestern:16709
-
- Description:
- Light is a powerful tool for manipulating and probing magnetic states in solid state systems. In particular, optically-induced spin orientation, the ability to orient spin with polarized light, has been extensively utilized in low-dimensional III-V and II-VI semiconductors to pioneer spintronic research. Even though traditional semiconductors have found a wide...
- Keyword:
- Layered Semiconductors, Optical Spin Dynamics, Monochalcogenides, van der Waals Systems, and Magneto-optics
- Subject:
- Physics and Condensed matter physics
- Creator:
- Nelson, Jovan Julius
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_982678 and http://dissertations.umi.com/northwestern:16502
-
- Description:
- A proliferation of new media platforms have upended the traditional roles that journalists have played in society, placing their work into content streams that are populated by creators who mimic the surface features of their work but not their methods. As a result, journalists’ practices and news media that they...
- Keyword:
- News Literacy, Pedagogy, Journalism Education, Boundary Setting, and Constructivism
- Subject:
- Journalism, Educational philosophy, and Education
- Creator:
- Spikes, Michael Antonio
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1009657 and http://dissertations.umi.com/northwestern:16690
-
- Description:
- We present a biophysical model of GCaMP6f calcium fluorescence in CA1 pyramidal neuron dendrites based upon results from imaging and electrophysiology experiments. This work was completed using experimental results from the laboratory of Professor Daniel Dombeck, Department of Neurobiology. Constraining the model to reproduce different objectives --- from in-vitro and...
- Keyword:
- Calcium Model, Dendritic Spines, Computational Neuroscience, Calcium Imaging, and Synaptic Integration
- Subject:
- Applied mathematics and Neurosciences
- Creator:
- Young, Brita Schneiders
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_819855 and http://dissertations.umi.com/northwestern:15589
-
- Description:
- In this paper, we study the basic locus in the fiber at $p$ of a certain unitary Shimura variety with a certain parahoric level structure. The basic locus $\widehat{\CM^{ss}}$ is uniformized by a formal scheme $\CN$ which is called Rapoport-Zink space. We show that the irreducible components of the induced...
- Subject:
- Mathematics
- Creator:
- Cho, Sungyoon
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14572 and etdadmin_upload_657697
-
- Description:
- As of 2020, there are currently 5.8 million people in the United States suffering from Alzheimer’s Disease (AD), a debilitating and progressive neurodegenerative disorder. Of these nearly six million people, two-thirds are women. While it has been suggested that women’s longer lifespan accounts for this disparity, the overall lifetime risk...
- Subject:
- Neurosciences
- Creator:
- Dominguez, Sky
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_971823 and http://dissertations.umi.com/northwestern:16455
-
- Description:
- We investigated the relationships between trauma, depression, and pelvic pain severity in patients with chronic pelvic pain. Previous research has demonstrated that pelvic pain is associated with trauma history (e.g., physical and sexual abuse). As one potential mechanism of this relationship, trauma may lead to increased susceptibility to pain by...
- Keyword:
- trauma, catastrophizing, chronic pelvic pain, urologic chronic pelvic pain syndromes (UCPPS), depression, and pain severity
- Subject:
- Clinical psychology
- Creator:
- Taple, Bayley Jane
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15601 and etdadmin_upload_823488
-
- Description:
- Down syndrome occurs in approximately 1 in 700 births annually in the United States. It is caused by trisomy of chromosome 21, and is characterized by dysmorphic features and congenital abnormalities. Although children with DS have a decreased risk of developing solid tumors, they have an increased risk of acquiring...
- Keyword:
- DYRK1A, B-ALL, FOXO1, and STAT3
- Subject:
- Oncology and Biology
- Creator:
- Rammohan, Malini Krishna
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15335 and etdadmin_upload_771926
-
- Description:
- In this dissertation, we aim to develop a theoretical understanding of foundation models and reinforcement learning. We delve into a comprehensive analysis of specific aspects within these domains. The focal points of our study are as follows: • Generative Adversarial Imitation Learning (GAIL) with Neural Networks: GAIL is poised to...
- Keyword:
- Reinforcement Leanring, In-Context Learning, Imitation Leanring, and Transformer
- Subject:
- Statistics and Operations research
- Creator:
- Zhang, Yufeng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013414 and http://dissertations.umi.com/northwestern:16740
-
- Description:
- Mitochondrial complex I is the primary entry point for electrons into the mitochondrial electron transport chain that is composed of 45 individual protein subunits that are encoded in both the nuclear and mitochondrial genomes. Mitochondrial complex I sits at an important nexus in the essential bioenergetic, biosynthetic, and signaling functions...
- Keyword:
- NDI1, NDUFS2, NDUFS4, Mitochondria, Leigh Syndrome, and Metabolism
- Subject:
- Biology, Aging, and Neurosciences
- Creator:
- McElroy, Gregory Scott
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_746970 and http://dissertations.umi.com/northwestern:15152
-
- Description:
- This thesis studies Bayesian-robustness of algorithm design. The main perspective requires for a single fixed algorithm that its performance is an approximation of the optimal performance when its inputs are independent and identical draws (i.i.d.) from every unknown distribution which is an element of a known, large class of distributions....
- Keyword:
- prior independent algorithms, benchmark design, lower bounds, and mechanism design
- Subject:
- Computer science
- Creator:
- Johnsen, Aleck
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_845328 and http://dissertations.umi.com/northwestern:15766
-
- Description:
- Parasitic nematode infections are common in both humans and livestock populations around the globe. In humans, these infections cause illness which can be debilitating. In livestock, parasitic nematode infections result in poor animal health and wellbeing as well as decreases in the yield of these animals. The decrease in yield...
- Keyword:
- Parasites, Anthelmintics, beta-tubulin, and C. elegans
- Subject:
- Molecular biology and Genetics
- Creator:
- Dilks, Clayton Matthew
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15713 and etdadmin_upload_843341
-
- Description:
- Wireless power strategies are critical to system level implementation of bio-integrated devices. To achieve mechanically robust, manufacturable systems, batteries are often integrated as an on-board power source to support sensing, wireless communication and signal conditioning. Unfortunately, most sources of battery power use hazardous and environmentally harmful materials, which frustrate incorporation...
- Subject:
- Chemistry, Materials Science, and Biomedical engineering
- Creator:
- Huang, Ivy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_934213 and http://dissertations.umi.com/northwestern:16294
-
- Description:
- Cancer remains a leading cause of death worldwide, necessitating continued study to explore and unravel its complex etiology. For example, there has been a shift of focus in cancer treatment from surgery and radiotherapy to targeted chemo- and immunotherapies as we gain more knowledge on the hallmarks of cancer (e.g.,...
- Keyword:
- tumor microenvironment, nanomedicine, Checkpoint inhibitor, spherical nucleic acids, gene expression/knockdown, and immunotherapy
- Subject:
- Nanotechnology, Oncology, and Immunology
- Creator:
- Chou, Liyushang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_884998 and http://dissertations.umi.com/northwestern:15965
-
- Description:
- Rivers and streams play a critical role in connecting major global carbon pools – land, oceans, and atmosphere. The longitudinal flow in rivers and streams allows for the integration and transport of fluvial particulate organic carbon (POC) from various sources and its continual transformation. A continuum-oriented perspective suggests longitudinal variations...
- Keyword:
- biomarker, particulate organic carbon, storm, stream, and agricultural watershed
- Subject:
- Environmental science and Biogeochemistry
- Creator:
- Kim, Jieun
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16775 and etdadmin_upload_1014167
-
- Description:
- The study of magnetic frustration has attracted considerable interest in the fields of materials science and condensed matter physics. Artificial Spin Ices (ASIs) are the primary systems in which magnetic frustration has been studied. To date, most studies on ASIs have been on fully periodic systems. In this thesis, we...
- Keyword:
- Lorentz Microscopy, Magnetic Materials, Artificial Spin Ice, and Magnetic Imaging
- Subject:
- Materials Science
- Creator:
- Brajuskovic, Vuk
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_677615 and http://dissertations.umi.com/northwestern:14759
-
- Description:
- On-shell formulations of scattering amplitudes for quantum field theories, without utilizating the local descriptions of Lagrangian and Feynman diagrams, have become increasingly useful and important in recent years for both formal and practical reasons. The nonlinear sigma model (NLSM), which describes the interactions between Nambu-Goldstone bosons, is an ideal testing...
- Keyword:
- Soft bootstrap, Effective field theory, Nonlinear sigma model, Soft theorem, and Scattering amplitude
- Subject:
- Physics
- Creator:
- Yin, Zhewei
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_750160 and http://dissertations.umi.com/northwestern:15166
-
- Description:
- Owing to policy action as well as continued cost declines, solar and wind resources are projected to play a central role in many future electricity systems. Since the technological characteristics and cost structures of these resources differ significantly from traditional thermal technologies, many have questioned how market designs will need...
- Keyword:
- Market design and Power systems
- Subject:
- Operations research
- Creator:
- Mays, Jacob
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14660 and etdadmin_upload_662781
-
- Description:
- This dissertation addresses problems in the source properties of major earthquakes. It is composed of four largely independent studies. In chapter 2, we explore the possible theoretical origin of the distance-depth correction q(, h) introduced 75 years ago by B. Gutenberg for the computation of the body wave magnitude mb,...
- Subject:
- Geophysics
- Creator:
- Saloor, Nooshin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_720180 and http://dissertations.umi.com/northwestern:15019
-
- Description:
- The treatment of AML remains to be a challenge due to the high rates of resistance and relapse experienced by patients after initial therapy. The MAPK-interacting kinases 1 and 2 (MNK1/2) have generated increasing interest as therapeutic targets for AML due to their critical role in malignant hematopoietic transformation via...
- Subject:
- Molecular biology, Biology, and Biochemistry
- Creator:
- Suarez Palacios, Milagros Melanie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_845430 and http://dissertations.umi.com/northwestern:15772
-
- Description:
- The goal of the work reported here was to answer two important questions with regards to LTVV use for patients with ARDS: 1) How do we measure adoption? and 2) What are the drivers of provider adoption? To this end, I have demonstrated the influence of patient height, hypoxemia severity,...
- Keyword:
- data science, low tidal volume ventilation, network science, implementation science, and acute respiratory distress syndrome
- Subject:
- Biomedical engineering and Medicine
- Creator:
- Bechel, Meagan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/29/2020
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14975 and etdadmin_upload_716010
-
- Description:
- Understanding the complex genome-phenome associations behind human complex traits will be a primary focus for the practice of precision medicine in the future. Identifying the genetic variants that contribute to the inter- and intra- phenotypic variations of individuals, elucidating pleiotropic architecture of common complex traits, and demonstrating how personal biomedical...
- Keyword:
- Electronic Health Records, Genome-wide association studies, Bioinformatics, Biomedical Informatics, Precision medicine, and Phenome-wide association studies
- Subject:
- Bioinformatics, Genetics, and Medicine
- Creator:
- Joo, Yoonjung Yoonie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_719309 and http://dissertations.umi.com/northwestern:15009
-
- Description:
- Blockchains are an exciting new type of Peer-to-Peer (P2P) distributed systems, which enable parties to transact directly, and maintain the record of said interactions in a distributed manner. A unique feature of blockchains is their ability to maintain a consensus without requiring knowledge on the number of participants, nor their...
- Keyword:
- Blockchain Distribution Network, Distributed Systems, Blockchain Scalability, Blockchain, Layer-0, and Relay Networks
- Subject:
- Computer science
- Creator:
- Klarman, Uri
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14514 and etdadmin_upload_638535
-
- Description:
- In multiatomic systems, high applied pressures reduce interatomic contact distances. At pressures comparable to those inside planets, this relatively simple principle completely changes the guiding principles of chemistry and physics established at near-ambient conditions. High-pressure investigations of precisely how the laws of nature evolve in the gigapascal and megabar regime...
- Keyword:
- Magnetism, Jarosite, Mineral Physics, High Pressure, BiVO3, and Synthesis
- Subject:
- Inorganic chemistry
- Creator:
- Klein, Ryan Alexander
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14839 and etdadmin_upload_686360