Each neuron in the primary motor cortex (M1) is like a musician in an orchestra, contributing to a larger harmony under the constraint of a “neural manifold”—a geometric score describing the correlated signals produced by the neural musicians that drive movement. Despite the widespread recognition of the importance of M1...
In the late 2000’s, scientific studies in cultural heritage saw a great advancement in macro X-ray fluorescence (XRF) imaging of paintings. These images are used to generate elemental distribution maps, which aid in identifying chemical elements and paint pig- ments as well as their locations throughout the layers of the...
In this document, I demonstrate that: 1) Linear basis functions cannot outperform nonlinear ones to represent hand kinematics 2) Nonlinear autoencoders outperform PCA on the dimensionality reduction of hand kinematics, 3) Nonlinear autoencoders outperform PCA in human gait representation and recurrent nonlinear autoencoders can seamlessly express the temporal dynamics, 4)...
In 2009, the Health Information Technology for Economic and Clinical Health Act (HITECH) promoted national use of electronic health records (EHR) in the US by giving incentives to providers who adopt ‘meaningful use’ of EHRs. As of 2017, nearly 86% of office-based physicians had adopted EHRs. EHRs have rich information...
In recent years, machine learning on graphs (or networks) has gone from a niche topic with only a few active researchers worldwide, to a heavily invested field with novel use cases for dealing with relationships and/or interactions within complex systems in the natural and social sciences. Traditionally, choosing the right...
Mixing by cutting-and-shuffling (like that for a deck of cards or a Rubik's cube) is a paradigm that has not been studied in detail even though it can be applied in a variety of situations including the mixing of granular materials. Mathematically, cutting- and-shuffling is described by piecewise isometries (PWIs),...
In the U.S., approximately 840,000 Americans die from cardiovascular disease (CVD) each year, and it is the leading cause of morbidity and mortality worldwide. The prevalence of CVD is on the rise and widespread disparities in CVD exist across economic, racial, and ethnic groups. In order to address the rising...
The task of classification has been increasingly attracting attention from researchers in recent years. The objective is to assign labels given attributes of samples. The classification task is practical in real-world applications and is widely explored in fields such as computer vision, natural language processing and information retrieval. The recent...
This dissertation asks how researchers can create more equitable algorithmic systems. Ultimately, this thesis explores methods and implications of representing subjects of analysis in the design and evaluation of algorithmic systems. I also unpack how algorithmic tools measure and quantify human behavior, giving heed to the potential impacts of these...
Computational imaging (CI) is a class of imaging systems that optimize both the opto-electronic hardware and computing software to achieve task-specific improvements. Machine/deep learning models have proven effective in drawing statistical priors from adequate datasets. Yet when designing computational models for CI problems, physics-based models derived from the image formation...