Abstract A significant component of the repetitive dynamics during locomotion in vertebrates is generated within the spinal cord. The legged locomotion of mammals is most likely controled by a hierarchical, multi-layer spinal network structure, while the axial circuitry generating the undulatory swimming motion of animals like lamprey is thought to...
Circadian rhythms — physiological, behavioral, and metabolic oscillations with an approximate 24-h period — are controlled by an evolutionarily conserved set of core clock genes operating at the transcriptional and protein level. Entrainable by Zeitgebers (external environmental stimuli such as light, temperature, and food) that modulate time-of-day specific functions, the...
This data was a part of a REDCap survey opened from 5/6/2020 to 7/7/2020. Potential participants with cerebral palsy and their families voluntarily responded to various questions about the motivators, barriers, and goals associated with the decision to participate in cerebral palsy research. Included in this work are the dataset...
Throughout the last two decades several scholars observed that present-day research into human genes rarely turns toward genes that had not already been extensively investigated in the past. Guided by hypotheses derived from studies of science and innovation, we present here a literature-wide data-driven meta-analysis to identify the specific scientific...
This is the raw data for an article in the process of being published. The article's abstract is: There is evidence suggesting that during walking the whole body center-of-mass (COM) trajectory may be a control objective, a goal that the central nervous system chooses optimal solutions around to plan and...
Background: Neural impairments that follow hemiparetic stroke may negatively affect passive muscle properties, further limiting recovery. However, factors such as hypertonia, spasticity, and botulinum neurotoxin (BoNT), a common clinical intervention, confound our understanding of muscle properties in chronic stroke.
Objective: To determine if muscle passive biomechanical properties are different following...
This study is in consideration of the spread of COVID-19, the related various government responses, and how these responses and other demographic variables affected the spread and severity of the virus on a domestic (United States) and international level. During the last few months, the virus has spread from its...
Background
Over-testing and overtreatment in older adults may lead to harm. Clinician decision support redirecting attention to possible harms and engaging social and reputational concerns might reduce overuse.
Methods
We performed an 18-month pragmatic cluster-randomized trial in 60 primary care practices with 371 clinicians, comparing behavioral-science-informed point-of-care clinical decision support...