Metal–organic frameworks (MOFs) are a class of crystalline materials composed of metal nodes connected by organic linkers. Due to their high degree of synthetic tunability, MOFs have been considered for a wide range of applications, including many that rely on a change in oxidation state. While most MOFs are generally...
Molybdenum oxides and sulfides are earth-abundant materials known to catalyze a wide array of reactions, including dehydrogenation, hydrotreating, and higher alcohols synthesis. In particular, alkane and alcohol dehydrogenation are of interest given recent shifts in the energy landscape away from traditional petroleum feedstocks and towards natural gas and renewable energy...
Metal-organic frameworks are crystalline, nanoporous materials formed by metal nodes connected by organic ligands. MOFs represent an exciting approach to materials design where a material with desired properties can be made by choosing the compatible nodes, linkers and topologies independently. MOFs are highly porous and have high surface areas...
Cells are primarily comprised of metal ions, small molecules, proteins, lipids, and nucleic acids. The ability to probe these molecules in single living cells can shed new light on chemical processes inside of cells or allow disease diagnosis based on molecular profiling. However, there exists a lack of tools that...
The Escherichia coli ribosome is a molecular machine capable of sequence-defined polymerization of -amino acids into proteins, a feat unmatched by any other current synthetic catalyst. It is complex in its structure, comprised of 3 RNA parts (the 5S, 16S, and 23S ribosomal RNAs) and 54 ribosomal proteins (r-proteins). Efforts...
By 2030, up to half of the world’s population is projected to suffer from water insecurity: a chronic scarcity of potable water due to rapidly warming temperatures, increased agricultural demand, and pollution. The health impacts of contaminated water are profound: hundreds of thousands of global deaths each year are ascribed...
While metabolic engineering can enable the sustainable bioproduction of new materials, efforts are often impeded by pathway bottlenecks. To mitigate the effects of toxic or reactive intermediates and resource competition resulting from heterologous pathway incorporation, bacterial microcompartments (MCPs) have recently been considered for engineered compartmentalization in bacterial host organisms. MCPs...
Two-step, solar thermochemical water splitting using nonstoichiometric oxides has emerged as an attractive approach for large-scale hydrogen production. Perovskite-structured oxides, with their wide tunability, offer the potential for high fuel productivity at moderate operating temperatures. Given the vast chemical space, the materials development effort is carried out here in combination...
Interfacial effects play a critical role in perturbing the properties of polymeric materials. The average properties of polymer materials with substantial specific interfacial area, e.g., ultrathin films, nanorods, and polymer nanocomposites, often deviate significantly from the bulk responses. Much of the past research has focused on systems in which free...
The need to rapidly develop and produce life-saving vaccines and therapeutics is critical for overcoming pandemics in a global economy. Recent advances in automation and cell-free systems have opened new avenues for expediting optimization and production of biologic vaccines and therapeutics. A key consideration for the development of protein biologics...