Light provides a high-speed and coherent medium for controlling quantum states. In semiconductors, coherent optical effects have been used extensively to lift spin degeneracy on ultrafast timescales and demonstrate high-fidelity control of quantum spin states. Extending this approach to novel pseudospins in monolayer transition metal dichalcogenides (TMDs), in this thesis...
This dissertation explores ways to utilize physical parameters at the nanoscale interface to control the properties of mixed-dimensional heterojunctions (MDHJs). MDHJs combine the desirable properties of different classes of low-dimensional nanomaterials (materials that are quantum confined in at least one dimension). While MDHJs have achieved superlative performance for a variety...
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by motor neuron (MN) degeneration and resulting in progressive paralysis and death. ALS is genetically heterogeneous, disease pathophysiology is not completely understood, and there are no effective drug therapies. To develop broadly applicable therapeutics, we examine disease mechanisms in the...
Superconducting qubits are among the leading competitors in the race towards building the first full-fledged quantum computer. Using this platform, researchers have for the first time demonstrated computational capability that is beyond the reach of the current classical machines. (This achievement is nicknamed "Quantum Supremacy".) Up to date, however, the...
The nature of dark matter (DM) remains one of the largest open questions in modern physics despite the many searches for particle dark matter around the world. The search for dark matter particles with masses above 5 GeV/$c^2$ is led by the dual-phase xenon time-projection chamber (LXe-TPC) detector technology which...
My research goal is to develop first principles frameworks to interrogate multiphase, multiscale systems. One of my main focus areas is to consistently deconstruct highly nonequilibrium problems into their fundamental components. By using analytical, computational and experimental tools to grasp the key levers controlling such phenomenon, I aim to build...
A major distinction among different skeletal muscles in the human body is the number, size, and arrangement of its cells, referred to as a muscle’s architecture. Muscle architecture is indicative of a muscle’s ability to contract and produce force and, like muscle function, is plastic. While neuromuscular plasticity is the...
This dissertation asks how can researchers more equitably design sociotechnical interventions to support the information work of sheltered emerging adults. Through two research studies, I explore the technology use in fulfilling the information needs among this population as well as how their environment impacts their strengths and information practices. I...
In an era of personalized medicine, the clinical community has become increasingly focused on understanding diseases at the cellular and molecular level. Magnetic resonance imaging (MRI) is a powerful imaging modality for acquiring anatomical and functional information. However, it has limited applications in field of molecular imaging due to low...
Movement is achieved by combining synaptic inputs from various sources and activating motor unit populations. Motor units are the quantal elements of motor control which act as a neuromechanical transducer that converts sensory inputs into motor output. Because of the tight neuromuscular junctions between motoneuron axon terminals and a large...