Two-dimensional (2D) covalent organic frameworks (COFs) are a class of crystalline polymer networks that polymerize and crystallize into layered structures, characterized by their atomically precise structure, permanent porosity and high modularity. Imine-linked COFs are one of the most important and promising classes of macromolecular sheets, which form by the condensation...
Late talkers (LTs) are a heterogenous group of children who experience delayed language development in the absence of other known causes (Fisher, 2017). Many LTs “catch up” to their typically talking peers (TTs), but some go on to experience continued difficulties with speech and language development (Dale & Hayiou-Thomas, 2013),...
In this dissertation, advances are made in understanding both the way hyporheic exchange impacts riverbed morphodynamics and the physical processes that lead to turbulent momentum transfer in the first few grains of riverbed sediments. In terms of physical advances in understanding the interplay between bedform movement and hyporheic exchange, we...
Mammalian transcriptional regulation is well-known to be complex and highly context dependent. Different genetic and epigenetic features, including single nucleotide polymorphisms (SNPs) that function as cis- or trans-expression quantitative trait loci (eQTLs), transcription factor (TF) interaction profile with cis-regulatory elements (CREs), methylation of CpG dinucleotide sequences, and histone modification that...
Molecular-oriented single-site heterogeneous catalysis is a powerful approach to address the long-lasting challenge of the structure-activity relationship in catalysis, as it allows molecular level control of the catalytic centers and thus the elucidation of reaction mechanisms. In this dissertation, single-site molybdenum-dioxo species have been immobilized on carbon supports, i.e. activated...
The idea that structure determines the properties of a material is a powerful concept in chemistry and in all fields in which chemistry is important, including engineering, medicine, and materials science. My research aims to better understand the structure-property relationships of a class of materials known as metal–organic frameworks (MOFs)....
Interactions with pollinators are thought to be a major driver of the evolution and diversification of angiosperms, yet questions remain about how pollinators mediate plant divergence at early stages and across entire species distributions. Here, I address this knowledge gap using two study groups in the recently-radiating and florally diverse...
When first-year students begin college they are thrown into a new environment where they are expected to simultaneously perform academically, form new relationships, and become independent. Many students struggle with this transition; experiences of stress, anxiety, and depression are common. For the majority of residential college students this is their...
Circulating tumor cell (CTC) clusters mediate metastasis at a higher efficiency compared to single cells and are associated with lower overall survival in breast cancer. However, the cellular heterogeneity and molecular mechanisms underlying CTC cluster formation and metastasis have yet to be fully elucidated. Combining single-cell RNA sequencing and flow...
This dissertation consists of three chapters on topics in economic theory. In Chapter 1, "Subjective Complexity Under Uncertainty", I propose and axiomatize a model of choice under uncertainty in which the size of the partition with respect to which an act is measurable arises endogenously as a measure of subjective...