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- Description:
- In the first part of the thesis we,given a dg-Lie algebra $\g$, a commutative dg-algebra $A$ and a twisting cochain $\mu$ in $A \otimes \g$, we construct a map from the functor of curved deformations of $\g$ to the functor of curved deformations of the twisted tensor product $A \otimes_\mu...
- Keyword:
- L-infinity algebras, Lie coalgebra, A-infinity algebras, Period map, Quantization, and Deformation theory
- Subject:
- Mathematics
- Creator:
- Papayanov, Grigory
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_985714 and http://dissertations.umi.com/northwestern:16566
-
- Description:
- Neuroblastoma is one of the most common childhood cancers with one of the lowest survival rates, accounting for 15% of childhood cancer mortality. Approximately 15% of patients do not respond to initial treatment, and about half of children treated for high-risk neuroblastoma will relapse following remission. Ionizing radiation has long...
- Subject:
- Cellular biology
- Creator:
- Ritner, Carissa
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_977952 and http://dissertations.umi.com/northwestern:16470
-
- Description:
- Amyloid beta oligomers (AβOs) are a key instigator of neurodegeneration in Alzheimer’s disease (AD). The work presented in this thesis includes three disease-modifying approaches to disrupt pathological AβO-related mechanisms in AD: (1) inhibiting AβO buildup, (2) blocking AβO-induced tau phosphorylation, and (3) neutralizing AβOs. These three approaches were tested in...
- Keyword:
- Amyloid beta oligomer
- Subject:
- Chemistry
- Creator:
- Johnson, Elizabeth Anne
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16421 and etdadmin_upload_962600
-
- Description:
- Technology that processes text, audio and video, as well as location data, has revolutionized many industries by enabling innovative operations for customer retention. To retain transactions for a platform and viewers for advertisers, this dissertation leverages novel digital tools to analyze consumer behavior, proposes original economic frameworks to guide platform...
- Keyword:
- Ad Avoidance, Multimedia Data, Platform, Geolocation, Machine Learning, and Disintermediation
- Subject:
- Marketing, Economics, and Information technology
- Creator:
- Xie, Yingkang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16589 and etdadmin_upload_986414
-
- Description:
- The on-going demand for miniaturized optical and on-chip photonic systems of the future has led to a few potential solutions in the literature. Recent advances in van der Waals and 2-dimensional materials signal a bright future for the next generation, compact electronic and photonic devices. With reduced dimensionality and material...
- Keyword:
- Polarization, Phonons, van der Waals, Plasmons, Wave plate, and 2D materials
- Subject:
- Optics, Materials Science, and Electromagnetics
- Creator:
- Abedini Dereshgi, Sina
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16396 and etdadmin_upload_958293
-
- Description:
- Human communication has become increasingly reliant on systems made and managed by large technology companies like Google, Apple, Twitter, and Meta (formerly Facebook). These systems offer people many benefits, but they also present new challenges for society. In recent years, researchers, lawmakers, and journalists have suggested that large technology companies...
- Keyword:
- Apple, Twitter, Google, Algorithm Auditing, Sociotechnical Systems, and Facebook
- Subject:
- Artificial intelligence, Computer science, and Communication
- Creator:
- Bandy, Jack
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16555 and etdadmin_upload_985359
-
- Description:
- The retina detects light, processes the visual signal, and sends a complex set of parallel information channels to the brain via a functionally diverse set of retinal ganglion cells types. This manuscript examines these retinal ganglion cell types, the visual features they encode, and the computational mechanisms leading to their...
- Keyword:
- electrophysiology, computational, signal processing, Bipolar cell, Retina, and ganglion cell
- Subject:
- Ophthalmology and Neurosciences
- Creator:
- Swygart, David Isaiah
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_962145 and http://dissertations.umi.com/northwestern:16411
-
- Description:
- The esophagus plays a crucial role in the functioning of the gastrointestinal tract and esophageal disorders are associated with reduced quality of life. Several studies have reported that there is a high worldwide prevalence of esophageal disorders. Esophageal disorders are related to the mechanical properties and function of the esophageal...
- Subject:
- Mechanics, Artificial intelligence, and Biomechanics
- Creator:
- Halder, Sourav
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16567 and etdadmin_upload_985717
-
- Description:
- Nanomaterials present an exciting landscape of innovation at length scales below 100 nm, wherein controllable synthesis and materials metrology have led to tunable structure-property relationships and next-generation products. The disruptive field of nanotechnology is poised to capitalize upon the exotic chemistry and physics of these nanomaterials to enable more efficient...
- Keyword:
- graphene, scalable manufacturing, nanomaterials, nanomanufacturing, 2D materials, and electronic materials
- Subject:
- Nanotechnology, Materials Science, and Engineering
- Creator:
- Downing, Julia Rocio
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16548 and etdadmin_upload_985168
-
- Description:
- In Chapter 1, I analyze optimal capital structure using a model in which firms issue securities in order to (1) finance investments in operations and (2) recapitalize the firm. In this trade-off model, firms balance the tax benefits of debt against the costs of financial distress. Key to the analysis,...
- Subject:
- Economics and Finance
- Creator:
- Hu, Jingxiong
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_986275 and http://dissertations.umi.com/northwestern:16585