The construction of new C–C bonds remains a central facet of organic chemistry due to its critical role in the synthesis of pharmaceutical compounds and organic materials. Mild and selective methodologies are often required for efficient formation of these bonds in natural product total synthesis, medicinal chemistry campaigns, and more....
The discovery and tailoring of new useful organic molecules for applications such as medicine and materials science is highly driven by meaningful developments in chemical methodology, and some of the most impactful advances have invoked catalysis to increase efficiency and specificity. N-heterocyclic carbenes (NHCs) have continuously occupied a prominent space...