Black women performers have made, and continue to make, contributions to the U.S.-avant-garde performance canon and Black performance traditions that go largely unaccounted for in academic studies. Research has shown that across temporalities, Black women performers have mobilized experimental avant-garde aesthetics to disrupt and refuse essentialized notions of Blackness in...
Glioblastoma multiforme (GBM) is the most prevalent primary central nervous system tumor, characterized by resistance to therapeutic intervention, inevitable recurrence, and ultimately patient death. The dismal prognosis is due in part to underlying molecular factors that promote an intratumoral cellular state heterogeneity and protect tumor cells from cell death pathways....
A unifying concept across many fields, ranging from chemistry to architecture, is the bottom-up construction of sophisticated structures from simple building blocks. Materials with long-range order allow for consistent, predictable performance throughout the resulting structure. My research focuses on building highly ordered porous materials from atomic level building blocks based...
Since the invitation of ARPANet in 1969, network protocols and communication systems have continued to emerge. Especially in the past decade, the prosperity of mobile internet and cloud computing has resulted in a large number of network protocols and communication systems, which have become critical infrastructure for our society. Availability...
It is widely understood that people’s perceptions of themselves and tasks influence their engagement and effort. Further, these relationships are often viewed as the purview of the individual. In contrast, research on human development has documented the influences of participation in multiple (often overlapping) contexts on individual development. Processes of...
Models of recursive preferences are commonly associated with a preference for early resolution of uncertainty, often regarded as an important economic channel in applications. This dissertation provides a different understanding of recursive preferences based on attitudes toward correlation, and in particular aversion to intertemporally correlated risks. Part 1 provides a...
Prostate cancer is the most common cause of cancer among men in the United States, and the second most common cause of cancer-related death, accounting for significant morbidity and mortality. This dissertation describes the genomic landscape of prostate cancer from multiple angles to identify mechanisms of disease heterogeneity amongst patients....
This dissertation studies interactions between a non-Bayesian decision maker (DM) and a sophisticated information provider who wants to influence the DM. In the essay ``Strategic Justifications," an auditor receives a justification from a self-interested expert who wants to convince the auditor that she acted in good faith for her clients....
Zinc, an essential trace element that serves as an enzyme cofactor and can also be stored as a divalent ion in cellular vesicles, is emerging as an important mediator of signaling pathways required for biological functions such as growth, development, and reproduction. Zinc mediates cell signaling by acting both as...
Eukaryotic genomes are organized into chromatin, which acts to regulate access to the organism’s genetic material. A large and diverse class of proteins, known as chromatin modifiers and remodelers, are responsible for regulating the composition and structure of chromatin by monitoring nucleosomes. Chromatin remodelers are involved in multiple cellular processes,...