The active participation of external entities in the design and manufacturing flow has produced numerous hardware security issues. Among all the hardware security problems, piracy and overproduction are likely to be the most ubiquitous and expensive ones. Most leading-edge design houses have outsourced their fabrication to the offshore foundries for...
The goal of the work reported here was to answer two important questions with regards to LTVV use for patients with ARDS: 1) How do we measure adoption? and 2) What are the drivers of provider adoption? To this end, I have demonstrated the influence of patient height, hypoxemia severity,...
Researchers and educators have argued that productive learning may occur when young people have freedom to organize their activity based on their own interests and concerns. Schools increasingly provide “makerspaces” that allow students to design and build objects and technical devices of their choosing, and researchers have developed in-school programs...
This dissertation studies three topics in 19th and early 20th century economic history. Chapter 1 studies the causes behind low inter-regional migration from the American North to the South prior to the Civil War. Chapters 2 and 3 focus on topics in the economic history of Egyptian agriculture. Chapter 2...
Animals must establish the correct form during development. Regeneration is a process by which some animals reestablish their form following injury. This process requires both the generation of new missing cells after injury, and information to pattern new cells to reestablish the correct form. Planarian flatworms have an almost unlimited...
Techniques for achieving complete quantum control over atoms have been developed and perfected over the past four decades with great success. This work has led to multiple Nobel prizes and has been the catalyst for rapid advances in a broad array of research fields. A natural progression forward is to...
The ribosome, the cell’s machine for synthesizing proteins, can be thought of as the chef of the cell. Just as a chef reads a recipe and combines ingredients to create a dish, the ribosome reads cellular instructions and connects building block molecules (amino acids) to construct proteins. Like the final...
Chapter 1: Telomerase is a ribonucleoprotein enzyme that counteracts the shortening of telomeres by catalyzing the addition of nucleotides to the 3’ ends of chromosomes, resulting in telomerase inhibition attracting interest as a strategy for cancer. Telomerase has also been implicated in other tumorigenic pathways such as DNA damage repair,...
Foreign currency debt has led to many crises in emerging markets. In the past decade, firms in emerging economies have drastically increased their foreign currency borrowing, making them significantly exposed to depreciation shocks. To reduce their exposure to external shocks, central banks have increased their use of regulation, such as...
Superalloys strengthened by γ′(L12)-precipitates in γ(f.c.c.)-matrix exhibit superior high temperature mechanical properties and environmental resistance over long periods of operation, making them ideal candidates for aerospace and energy conversion applications. The emerging class of superalloys based on Co-Al-W ternary system was identified with a melting temperature 50-100 ˚C higher than...