The potential association between Female Genital Mutilation (FGM) and the incidence of Human Immunodeficiency Virus (HIV) has been a part of academic discourse for three decades. By considering the mixed reports on the association between FGM and HIV so far, this dissertation contributes to the current state of research by...
Levels of the several different human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) cytidine deaminases vary across different cell types. While levels of nuclear-localized A3s are low or non-existent in primary cells, a nuclear A3 is often upregulated in cancer cells. Increased chromosomal mutagenesis due to nuclear A3...
Abstract Kaposi sarcoma (KS) is the most common cancer associated with human immunodeficiency virus/ Acquired Immunodeficiency Syndrome (HIV/AIDS) infection worldwide and it is the most prevalent cancer in some countries in sub-Saharan Africa (SSA). The introduction of combination antiretroviral therapy (ART), led to dramatic declines in KS morbidity and mortality,...
Women living with human immunodeficiency virus (WLWH) have unique health challenges. Understanding psychological strengths that help WLWH manage their disease and improve health outcomes could reduce disease burden. Although spirituality, a multidimensional construct that includes a search for meaning and purpose, connection with a higher dimension, and experiences and feelings...