Northwestern University

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Filtering by: Creator Brazee, Patricia Resource type Dissertation Subject Immunology

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LUBAC activity regulates the lung epithelial response to influenza A virus infection

Description:

During influenza A virus (IAV) infection, severe lung injury and death result from an exuberant host inflammatory response, or “cytokine storm”, orchestrated by pulmonary epithelial cells. The linear ubiquitin assembly complex (LUBAC), composed of SHARPIN, HOIL-1L and HOIP, is a critical regulator of NF-κB-dependent inflammation. To determine the impact of...

Subject:

Immunology

Creator:

Brazee, Patricia

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

04/29/2020

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14980 and etdadmin_upload_716742