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Filtering by: Creator Chu, Lan Hoang Keyword Non-canonical inflammasome Resource type Dissertation Subject Immunology

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1. The Oxidized Phospholipid oxPAPC Inhibits the Non-canonical Inflammasome in Macrophages

Description:: Inflammasomes are signaling complexes that link the recognition of pathogen and danger associated molecular patterns (PAMPs and DAMPs) by cytosolic pattern-recognition receptors (PPRs) to the activation of Caspase-1, leading to the release of the pro-inflammatory cytokines interleukin (IL)-1 and IL-18, and the induction of pyroptosis. In addition to the canonical...
Keyword:: Caspase-11, oxPAPC, Sepsis, and Non-canonical inflammasome
Subject:: Immunology
Creator:: Chu, Lan Hoang
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_638156 and http://dissertations.umi.com/northwestern:14507