Northwestern University

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Filtering by: Creator Chu, Lan Hoang Subject Immunology

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The Oxidized Phospholipid oxPAPC Inhibits the Non-canonical Inflammasome in Macrophages

Description:

Inflammasomes are signaling complexes that link the recognition of pathogen and danger associated molecular patterns (PAMPs and DAMPs) by cytosolic pattern-recognition receptors (PPRs) to the activation of Caspase-1, leading to the release of the pro-inflammatory cytokines interleukin (IL)-1 and IL-18, and the induction of pyroptosis. In addition to the canonical...

Keyword:

Caspase-11, oxPAPC, Sepsis, and Non-canonical inflammasome

Subject:

Immunology

Creator:

Chu, Lan Hoang

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_638156 and http://dissertations.umi.com/northwestern:14507