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Filtering by: Creator Gutierrez Diaz, Blanca Teresa Resource type Dissertation Subject Molecular biology Subject Oncology

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1. Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Acute Leukemia

Description:: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease, affecting children and adults. Chemotherapy regimens show high response rates but have debilitating effects and carry risk of relapse. Until now, no targeted therapy has been approved. In addition, 40% of patients will relapse and their treatment options are limited because...
Keyword:: USP11, LCK, USP7, glucocorticoid, leukemia, and ubiquitination
Subject:: Molecular biology, Oncology, and Biochemistry
Creator:: Gutierrez Diaz, Blanca Teresa
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/02/2022
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_862777 and http://dissertations.umi.com/northwestern:15858