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Filtering by: Creator Julius B. Lucks Keyword synthetic biology

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Computational design of Small Transcription Activating RNAs (STARs) for versatile and dynamic gene regulation

Description:

A longstanding goal of synthetic biology has been the programmable control of cellular functions. Central to this is the creation of versatile regulatory toolsets that allow for programmable control of gene expression. Of the many regulatory molecules available, RNA regulators offer the intriguing possibility of de novo design – allowing...

Keyword:

transcription, RNA, RNA engineering, synthetic biology, and gene regulation

Subject:

Synthetic Biology and RNA engineering

Creator:

Matthew Verosloff, Alexandra Westbrook, James Chappell, and Julius B. Lucks

Owner:

Julius Beau Lucks

Publisher:

MacMillan Publishers

Language:

English

Date Uploaded:

08/03/2017

Date Modified:

01/07/2020

Date Created:

2017-08-03

Resource Type:

Dataset

Alternate Identifier:

doi:10.21985/N28S9B
Design and optimization of a cell-free atrazine biosensor

Description:

Recent advances in cell-free synthetic biology have spurred the development of in vitro molecular diagnostics that serve as effective alternatives to whole-cell biosensors. However, cell-free sensors for detecting manmade organic water contaminants such as pesticides are sparse, partially because few characterized natural biological sensors can directly detect such pollutants. Here,...

Keyword:

biosensor, TX-TL, atrazine, cell-free, cyanuric acid, metabolism, synthetic biology, and transcription factor

Creator:

Umut Akova, Khalid K. Alam, Michael C. Jewett, Julius B. Lucks, and Adam D. Silverman

Owner:

Adam Silverman

Date Uploaded:

09/23/2019

Date Modified:

02/19/2020

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Computational design of Small Transcription Activating RNAs (STARs) for versatile and dynamic gene regulation

Design and optimization of a cell-free atrazine biosensor

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