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Filtering by: Creator Kathryn Harris Gunn Type Work Keyword DNA Topology Keyword Fluorescence Subject Interdepartmental Biological Sciences (IBiS) Graduate Program

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1. Mechanistic Studies of Type IA and IIA Topoisomerases Using Orthogonal Single-Molecule Techniques

Description:: Topoisomerases are ubiquitous enzymes involved in maintaining the supercoiled state of DNA in the cell. Structural, biophysical, and biochemical studies have provided an overall view of the mechanisms of DNA transformation by these enzymes, but many aspects, particularly their dynamic characteristics, remain poorly understood. Type IA topoisomerases change the topology...
Keyword:: Fluorescence, Enzyme Mechanism, Magnetic Tweezers, Single-Molecule, Topoisomerase, and DNA Topology
Subject:: Interdepartmental Biological Sciences (IBiS) Graduate Program
Creator:: Kathryn Harris Gunn
Owner:: Scholarly Digital Publishing
Date Uploaded:: 04/13/2018
Date Modified:: 01/28/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

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1. Mechanistic Studies of Type IA and IIA Topoisomerases Using Orthogonal Single-Molecule Techniques