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Filtering by: Creator Matthew Ryan Reynolds Keyword Monoclonal Antibody Keyword Nitration Subject Neuroscience Institute Graduate Program

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1. Site-Specific Nitration of Tau in Alzheimer's Disease

Description:: Alzheimer's disease (AD) is a progressive amnestic dementia typified by the pathological self-association of the microtubule-associated tau protein into neurofibrillary tangles (NFTs). Important to NFT formation are numerous modifications of tau, including phosphorylation, truncation, and conformational changes. In addition, AD-associated inflammation promotes the formation of peroxynitrite (ONOO-), a potent nitrating...
Keyword:: Monoclonal Antibody, 3, 3'-Dityrosine, Nitration, Peroxynitrite, Alzheimer's, and Tau
Subject:: Neuroscience Institute Graduate Program
Creator:: Matthew Ryan Reynolds
Owner:: Scholarly Digital Publishing
Date Uploaded:: 07/26/2018
Date Modified:: 07/26/2018
Date Created:: 2007-05-14
Resource Type:: Dissertation