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Filtering by: Creator Nichole LaPointe Type Work Keyword axonal transport Subject Neuroscience Institute Graduate Program

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1. The N-Terminus of Tau in Filament Formation and the Regulation of Axonal Transport: A Perspective on Tau Assembly and Toxicity

Description:: In several neurodegenerative diseases, the microtubule-associated protein tau self-aggregates to form filaments that accumulate in neurons and/or glia, although the relationship between tau aggregation and cell death is a subject of debate. The amino terminus of tau is involved in conformational changes that appear critical for filament formation, hinting at...
Keyword:: filament, axonal transport, kinesin, Alzheimer's disease, and tau
Subject:: Neuroscience Institute Graduate Program
Creator:: Nichole LaPointe
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/06/2018
Date Modified:: 09/06/2018
Date Created:: 2008-02-21
Resource Type:: Dissertation