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A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains

Description:

The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions. Two major contributing factors are: (1) the lack of statistical power from measuring the phenotypes of small numbers of individuals, and (2) the use of...

Keyword:

QTL mapping, fitness assays, high-throughput phenotyping, and C. elegans

Creator:

Rajarshi Ghosh, Johnathan R. Crissman, Justin P. Gerke, Leonid Kruglyak, Tyler C. Shimko, Joshua S. Bloom, Hannah S. Seidel, and Erik C. Anderson

Owner:

Chris Diaz

Publisher:

Genetics Society of America

Language:

English

Date Uploaded:

01/12/2017

Date Modified:

01/12/2017

Date Created:

2015-03-13

Resource Type:

Article

Alternate Identifier:

doi: 10.1534/g3.115.017178
A Powerful New Quanitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains

Description:

The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions. Two major contributing factors are: (1) the lack of statistical power from measuring the phenotypes of small numbers of individuals, and (2) the use of...

Keyword:

QTL mapping, fitness assays, high-throughput phenotyping, and C. elegans

Creator:

Rajarshi Ghosh, Erik C. Andersen, Jonathan R. Crissman, Leonid Kruglyak, Tyler C. Shimko, Joshua S. Bloom, Hannah S. Seidel, and Justin P. gerke

Owner:

Chris Diaz

Publisher:

Genetics Society of America

Date Uploaded:

04/28/2017

Date Modified:

04/28/2017

Date Created:

2015-05-01

Resource Type:

Article

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A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains

A Powerful New Quanitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains

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