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Filtering by: Creator Stephanie Valtierra Keyword prion Keyword Swi1 Subject Interdepartmental Neuroscience Program (NUIN)

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1. Using the [SWI+] prion to study protein misfolding, aggregation, and amyloid formation

Description:: Saccharomyces cerevisiae contains several epigenetic elements known as yeast prions. Our laboratory discovered the yeast prion [SWI+], whose protein determinant is Swi1, a subunit of the SWI/SNF chromatin-remodeling complex. Formation of [SWI+] results in abolishment of multicellular features and a partial loss-of-function phenotype of non-glucose carbon source usage. Our laboratory...
Keyword:: amyloids, protein aggregation, prion, Saccharomyces cerevisiae, Swi1, and prion domain
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Stephanie Valtierra
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/26/2018
Date Modified:: 10/26/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation