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Filtering by: Creator Stephanie Valtierra Resource type Dissertation

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Using the [SWI+] prion to study protein misfolding, aggregation, and amyloid formation

Description:

Saccharomyces cerevisiae contains several epigenetic elements known as yeast prions. Our laboratory discovered the yeast prion [SWI+], whose protein determinant is Swi1, a subunit of the SWI/SNF chromatin-remodeling complex. Formation of [SWI+] results in abolishment of multicellular features and a partial loss-of-function phenotype of non-glucose carbon source usage. Our laboratory...

Keyword:

amyloids, protein aggregation, prion, Saccharomyces cerevisiae, Swi1, and prion domain

Subject:

Interdepartmental Neuroscience Program (NUIN)

Creator:

Stephanie Valtierra

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/26/2018

Date Modified:

10/26/2018

Date Created:

2017-01-01

Resource Type:

Dissertation