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Filtering by: Creator Tatyana A Klimova Keyword p53 Keyword senescence Subject Integrated Graduate Program in the Life Sciences

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1. Mechanisms of hyperoxia-induced senescence in primary human lung fibroblasts

Description:: Senescence, permanent, irreversible replication arrest that occurs in all primary cells studied to date, is considered a cellular model of aging. Recently, senescence has gained attention as a potential tumor-suppressing mechanism. However, despite the obvious importance of senescence, its exact mechanisms remain unclear. One current hypothesis to explain senescence postulates...
Keyword:: aging, p53, hyperoxia, senescence, and reactive oxygen species
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Tatyana A Klimova
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/10/2018
Date Modified:: 09/10/2018
Date Created:: 2008-05-08
Resource Type:: Dissertation