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Filtering by: Creator William Edward Putzbach Keyword Cancer Keyword RNA Interference Keyword DISE Subject Driskill Graduate Training Program in Life Sciences

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1. Toxicity Mediated by Seed-Dependent Off-Target Effects in RNA Interference

Description:: Post-transcriptional gene silencing (PTGS) and, more specifically, RNA interference (RNAi) include the processes by which a small double-stranded RNA, 19 to 22 nucleotides (nts) long, negatively regulates the expression and/or translatability of a target RNA, which harbors reverse complementarity to that small RNA, by recruiting the so-called RNA-Induced Silencing Complex...
Keyword:: siRNA, RNA Interference, Cell Death, Cancer, shRNA, and DISE
Subject:: Driskill Graduate Training Program in Life Sciences
Creator:: William Edward Putzbach
Owner:: Scholarly Digital Publishing
Date Uploaded:: 04/01/2019
Date Modified:: 04/01/2019
Date Created:: 2018-01-01
Resource Type:: Dissertation

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1. Toxicity Mediated by Seed-Dependent Off-Target Effects in RNA Interference