Autism spectrum disorder (ASD) is a heritable, neurodevelopmental disorder characterized by social impairments and restricted and repetitive behaviors (American Psychiatric Association, 2013; Tick, Bolton, Happe, Rutter, & Rijsdijk, 2016), with a subset of first-degree relatives demonstrating a constellation of subclinical traits that are qualitatively similar to the defining features of...
Background: The way in which one perceives their visual world (i.e., bottom-up visual perception) and what one pays attention to in their surroundings (i.e., top-down attention), are critical to uncovering underlying thoughts and cognitions, and impact how one operates in the social world. Individuals with autism spectrum disorder (ASD), a...
Contactin associated protein like 2 (CNTNAP2) has emerged as a prominent susceptibility gene implicated in multiple complex neurodevelopmental disorders, including autism spectrum disorders (ASD), intellectual disability (ID), and schizophrenia (SCZ). The presence of seizure comorbidity in many of these cases, as well as inhibitory neuron dysfunction in Cntnap2 knockout (KO)...