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- Description:
- X-ray Fluorescence Microscopy (XFM) is a useful technique for study of biological samples. XFM was used to map and quantify endogenous biological elements as well as exogenous materials in biological samples, such as the distribution of titanium dioxide (TiO2) nanoparticles. TiO2 nanoparticles are produced for many different purposes, including development...
- Keyword:
- Nanotechnology, Xray Fluorescence Microscopy, Radiation Oncology, and Cancer Nanotechnology
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- Koshonna Brown
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 12/10/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Over the past decade significant advancements have been made across the field of cancer biology resulting in transformative new therapies. Despite these advancements, treatments for metastatic cancer remain relatively ineffective. Metastasis is coordinated by various types of “healthy†stromal cells in addition to the tumor cells themselves. This requires a...
- Keyword:
- Nanotechnology, High-Density Lipoprotein, Cancer Immunology, Pre-Metastatic Niche, Exosomes, and Tumor Microenvironment
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- Michael P Plebanek
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 11/24/2019
- Date Modified:
- 11/24/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- Graphene oxide (GO), a product of oxidative exfoliation of graphite powders, has received significant attention due to its excellent solution dispersibility, rich functionality, and ease of conversion to chemically modified graphene (also known as œreduced graphene oxide or œr-GO). These properties make GO an attractive building block for constructing various...
- Keyword:
- Nanotechnology, Two-dimensional materials, Carbon materials, Graphene, and Graphene oxide
- Subject:
- Materials Science and Engineering
- Creator:
- Che-Ning Yeh
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 10/28/2019
- Date Modified:
- 11/20/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- The assembly of nanoscale building blocks into larger ensembles with well-defined architecture has the potential to create entirely new classes of designer photonic and plasmonic metamaterials with unique properties not found in nature. Electromagnetic metasurfaces, or 2D metamaterials, operating at optical wavelengths are of particular interest due to ease of...
- Keyword:
- Nanotechnology, Nanoparticles, Nanopatterning, Directed Assembly, Self-Assembly, and Electron Microscopy
- Subject:
- Materials Science and Engineering
- Creator:
- BENJAMIN MYERS
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 10/08/2019
- Date Modified:
- 10/08/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- This project is comprised of primary source research on the field of semiconductor microscopy. We were interested in determining a more interdisciplinary application of this technology, as the most frequently cited applications are for defense purposes such as drug screening or infrared imaging. When we researched, we found that these...
- Keyword:
- Terahertz Spectroscopy, Semiconductors, Nanotechnology, and Lasers
- Subject:
- Electrical Engineering
- Creator:
- Nathaniel Coirier and Vivian Chen
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 06/03/2019
- Date Modified:
- 06/03/2019
- Date Created:
- 3/22/2019
-
- Description:
- The projected increase in the use of nanomaterials raises concerns about adverse impacts new technologies utilizing these materials may have on the environment. These concerns can be addressed from a chemical perspective by studying how emerging nanomaterials interact with biological systems. Fundamentally, the key interactions for nanomaterial uptake into a...
- Keyword:
- Nanotechnology, Sustainable, Nano/Bio, Polymers, and Biomimetic
- Subject:
- Chemistry
- Creator:
- Alicia McGeachy
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 04/09/2019
- Date Modified:
- 04/09/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- Plasmonic nanostructures are capable of trapping and confining light at the nanoscale, leading to interesting optical phenomena involving enhanced light-matter interactions. These responses arise in two forms: surface plasmon polaritons propagating on the surface of metal films and localized surface plasmons confined to the surface of metal nanoparticles. Plasmonic modes...
- Keyword:
- Nanotechnology, Plasmonics, Symmetry, Nanofabrication, Nanopatterning, and Lasers
- Subject:
- Materials Science and Engineering
- Creator:
- Michael Knudson
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 02/25/2019
- Date Modified:
- 02/25/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- Spinal cord injury occurs with a worldwide incidence of 13-33 cases per million per year, and more than 2.5 million patients worldwide suffer from spinal cord injury (SCI)-related disability (1, 2). Different methods have been attempted to promote axonal regeneration, including neurotrophin injection, hydrogel injection, olfactory ensheathing cells implantation and...
- Keyword:
- Nanotechnology, Cord Injury, Fibrosis, and Therapeutics
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- Suji Jeong
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 02/08/2019
- Date Modified:
- 02/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Nanoscale materials are demonstrating new properties and promising applications with each passing day. The fabrication of ever more complex and precise nanomaterials represents a continuing drive in the fields of physics, chemistry, and biology. Template-based approaches provide an attractive method of producing new inaccessible materials by modifying and confining older...
- Keyword:
- Nanotechnology, Nanoparticles, Nanowells, and Tantalum Oxide
- Subject:
- Chemistry
- Creator:
- Jeremy Barton
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 09/10/2018
- Date Modified:
- 09/10/2018
- Date Created:
- 2008-05-12
- Resource Type:
- Dissertation
-
- Description:
- Novel materials and nanostructures with superior electro-mechanical properties are emerging in the development of novel devices. Engineering application of these materials requires accurate electro-mechanical characterization, which in turn requires development of novel experimental techniques. This dissertation outlines the investigation of the mechanical and electrical properties of one-dimensional nanomaterials. One-dimensional nanomaterials...
- Keyword:
- Nanotechnology, Thin Film, Nanomaterial, Mechanical Property, and MEMS
- Subject:
- Mechanical Engineering
- Creator:
- Bei Peng
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 09/07/2018
- Date Modified:
- 09/07/2018
- Date Created:
- 2008-05-09
- Resource Type:
- Dissertation
-
- Description:
- Metal and bimetallic nanoparticles are of interest and are widely used in various applications because of their unique optical, electronic, and catalytic properties, which differ from those of their bulk counterparts. Better understanding of the thermodynamic and kinetic properties of nanoparticles and their underlying growth mechanisms can serve as a...
- Keyword:
- Nanotechnology, Electron Microscopy, and Materials Chemistry
- Subject:
- Materials Science and Engineering
- Creator:
- Lingxuan Peng
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 03/28/2018
- Date Modified:
- 03/28/2018
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The ability to track labeled cancer cells in vivo would allow researchers to study their distribution, growth and metastatic potential within the intact organism. Magnetic Resonance (MR) imaging is invaluable for tracking cancer cells in vivo as it benefits from high spatial resolution and absence of ionizing radiation. However, many...
- Keyword:
- Nanotechnology and Chemistry
- Subject:
- Interdepartmental Biological Sciences (IBiS) Graduate Program
- Creator:
- Nikhil Ram Mohan
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 02/20/2018
- Date Modified:
- 02/20/2018
- Date Created:
- 2016-01-01
- Resource Type:
- Dissertation
-
- Description:
- Biological therapeutics have revolutionized the way we treat cancer due to their ability to target tumors discriminately, leaving healthy cells unaffected. However, our inability to tailor the structure of biologics may hamper their optimization for efficacy. This lack of programmability contributes to factors such as immunogenic responses, inability to penetrate...
- Keyword:
- Nanotechnology, Cancer therapy, Synthetic biology, Synthetic chemistry, Protein engineering, and Protein scaffolds
- Subject:
- Bioengineering, Chemistry, and Chemical engineering
- Creator:
- Kimmel, Blaise Russel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_852716 and http://dissertations.umi.com/northwestern:15804
-
- Description:
- Proteins are the nanoscale building blocks of life. Their sophisticated but well-defined architectures result in complex biological functions, including ones involved in metabolism, photosynthesis, transcription, translation, and immunity. To study and improve upon the natural functions of proteins, it is desirable to develop methodology for organizing proteins into targeted architectures....
- Keyword:
- Nanotechnology, Protein, Sequence-encoded, DNA, Assembly, and Biomaterial
- Subject:
- Chemistry
- Creator:
- Winegar, Peter Henry
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_927993 and http://dissertations.umi.com/northwestern:16239
-
- Description:
- Nanocarriers are drug delivery vehicles that have at least one dimension at the nanoscale (10-9 m). Engineering the nanocarrier surface is a strategy for targeting drug delivery to specific cell types to enhance efficacy and minimize side effects. A useful analogy is to consider how the chassis of an automotive...
- Keyword:
- Nanotechnology, Glaucoma, Immunomodulation, Protein Adsorption, Nanocarrier Chassis, and Targeted Drug Delivery
- Subject:
- Pharmaceutical sciences, Materials Science, and Biomedical engineering
- Creator:
- Vincent, Michael Patrick
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15870 and etdadmin_upload_863441
-
- Description:
- Label-free assays, and particularly those based on the combination of mass spectroscopy with surface chemistries, enable high-throughput experiments of a broad range of reactions. However, these methods can still require the incorporation of functional groups that allow immobilization of reactants and products to surfaces prior to analysis. In this thesis,...
- Keyword:
- Nanotechnology, SAMDI, Surface chemistry, Microarray, Mass Spectrometry, and Reactions
- Subject:
- Chemistry, Biomedical engineering, and Chemical engineering
- Creator:
- Helal, Kazi Yasin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15011 and etdadmin_upload_719318
-
- Description:
- Spinal cord injury (SCI) is a devastating injury, which can be caused by motor vehicle accidents, violence, and non-traumatic causes. These injuries can leave patients with lifelong paralysis, as well as incontinence and life threatening autonomic dysreflexia. There is currently no FDA approved treatment for SCI. Spinal injury disrupts the...
- Keyword:
- Nanotechnology, Fibronectin, Spinal Cord Injury, Fibrosis, Mechanical Properties, and Gliosis
- Subject:
- Biology, Biomechanics, and Neurosciences
- Creator:
- Cooper, John Gregory
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14557 and etdadmin_upload_650745