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Filtering by: Type Work Keyword Natural products Subject Interdepartmental Biological Sciences (IBiS) Graduate Program

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Description:: Fungi have an immense untapped store of natural products, small molecules that can often be repurposed as pharmaceuticals. The genes that encode secondary metabolic machinery are often genomically co-localized into biosynthetic gene clusters. Because of the immense energetic costs that goes into producing the biosynthetic pathway and its products, strict...
Keyword:: LC-MS, NRPS, Natural products, Aspergillus nidulans, metabolomics, and HDAC
Subject:: Interdepartmental Biological Sciences (IBiS) Graduate Program
Creator:: Matthew Thomas Henke
Owner:: Scholarly Digital Publishing
Date Uploaded:: 02/20/2018
Date Modified:: 02/20/2018
Date Created:: 2016-01-01
Resource Type:: Dissertation

Description:: Methanobactins (Mbns) are a growing family of ribosomally produced, post-translationally modified natural products that exhibit a high affinity for copper. These compounds were initially identified in methanotrophic bacteria, which oxidize methane to methanol as their sole source of carbon. One of the key enzymes in this metabolic pathway, particulate methane...
Keyword:: Methanobactin, Biosynthesis, Copper homeostasis, Methanotrophy, Chalkophores, and Natural products
Subject:: Interdepartmental Biological Sciences (IBiS) Graduate Program
Creator:: Grace Eileen Kenney
Owner:: Scholarly Digital Publishing
Date Uploaded:: 01/10/2019
Date Modified:: 01/29/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

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