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Filtering by: Type Work Keyword chromatin Keyword nucleosomes Keyword epigenetics Keyword transcription regulation Subject Interdepartmental Biological Sciences (IBiS) Graduate Program

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1. Mapping the Mouse Nucleosome Landscape through Chemical Biology

Description:: Nucleosome organization influences gene activity by controlling DNA accessibility to transcription machinery. In this thesis, we have developed a chemical biology approach to determine mammalian nucleosome positions genome-wide. Using this strategy, we uncover surprising new features of nucleosome organization in mouse embryonic stem cells. In contrast to the prevailing model,...
Keyword:: histones, nucleosomes, epigenetics, chromatin, and transcription regulation
Subject:: Interdepartmental Biological Sciences (IBiS) Graduate Program
Creator:: Lilien Voong
Owner:: Scholarly Digital Publishing
Date Uploaded:: 04/26/2018
Date Modified:: 01/29/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

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1. Mapping the Mouse Nucleosome Landscape through Chemical Biology