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Peptoid Mimics of Helical, Cationic Antimicrobial Peptides: Studies of Structure-Activity Relationships, Synergy, and Mechanism

Description:

The growing worldwide threat of antibiotic-resistant pathogens has necessitated a constant search for new classes of antibiotics. Antimicrobial peptides (AMPs) are integral components of innate immunity in virtually every living organism, and, due to their proven efficacy over millions of years of evolution, are considered promising leads for new antibiotic...

Keyword:

electron microscopy, bacterial ultrastructure, antibacterial mechanism, fluorescence spectroscopy, functional synergy, and N-substituted glycine antibiotics

Subject:

Chemical and Biological Engineering

Creator:

Nathaniel Paul Chongsiriwatana

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/13/2018

Date Modified:

09/13/2018

Date Created:

2008-11-03

Resource Type:

Dissertation