This thesis discusses the synthesis, self-assembly, and conductivity properties of novel oligothiophene derivatives with an emphasis on how molecular structure effects the assembly. In order to facilitate self-assembly in conjugated molecules, specific non-covenant forces were included into the molecular design of several derivatives. First, an amphiphilic oligothiophene derivative consisting of...
The de novo design of bio-inspired materials with precisely controlled properties is challenging, but has potential applications in nano-biotechnology. Applications range from nanometer scaled assemblies to three-dimensional scaffolds for tissue engineering. Genetic engineering of protein-based polymers offers distinct advantages over traditionally synthesized polymers, de novo proteins can be produced with...
Articular cartilage is a type of connective tissue that protects the underlying bone from the compressive forces of daily activities. When cartilage is damaged via a traumatic event, chondral defects are formed and require medical intervention. However, current treatments are of inconsistent efficacy and only benefit a subset of patients....
Two main topics are addressed in this dissertation: (1) adhesion in hydrogels; (2) interfacial interactions between model glassy polymers. A self-assembly technique for the formation of hydrogels from acrylic triblock copolymer solutions was developed, based on vapor phase solvent exchange. Structure formation in the gels was characterized by small angle...