Research shows the increasing tendency of political considerations to influence decisions outside the context of politics. This work documents examples of partisan affiliation influencing judgments and behaviors – and often resulting in favoritism or discrimination – in ostensibly nonpolitical contexts such as the workplace, academia, and dating, among others. To...
Basal ganglia are a highly interconnected group of nuclei involved in motor control. The external globus pallidus (GPe) is a critical node within the basal ganglia circuit. While the prevailing basal ganglia circuit model assumes the GPe as merely a relay, phasic changes in the activity of GPe neurons during...
It is said across numerous disciplines, from biology to architecture to software engineering, that “form ever follows function.” This adage highlights the intimate relationship between structural characteristics and functional properties in many disparate fields of work. Here, we discuss how the catalytic activity and compressibility of metal–organic frameworks (MOFs) are...
Sight-singing skills are a key component in empowering choristers to make music independently. Advances in technology have made visual feedback displaying the accuracy of a sight-singing attempt available to singers. The purpose of this study was to examine the effects of computerized visual feedback provided by the SmartMusic interface on...
Deciphering the targets of axonal projections plays a pivotal role in interpreting neuronal function and pathology. Neuronal tracers are indispensable neurobiology tools for elucidating advanced functions and interactions between different subregions of the brain. Commercially available neuronal tracers include small molecule dyes, viruses, and synthetic nanoparticles. Among these options, viral...
Multiteam systems (MTSs), or teams of teams, have recently become a standard for collaboration—ranging from traditional office teams to those setting a course for Mars. Although leadership is often identified as a critical lever for effective MTS functioning and success, there is little research to inform the question of how...
Interpersonal hierarchies are one of the most fundamental structures by which human interactions are organized (Yu & Kilduff, 2019), and dual-strategies theory suggests that humans navigate these hierarchies through the use of dominance (force and coercion) or prestige (display of valued traits to gain respect; Maner & Case, 2016). In...
A variety of human diseases and pregnancy related disorders reflect endometrial dysfunction. However, rodent models do not share fundamental biological processes with the human endometrium, such as cyclic menstruation, and no existing human cell cultures recapitulate the cyclic interactions between endometrial stromal and epithelial compartments necessary for decidualization and implantation....
“Queer Correspondence: Form and Femininity in the Long Eighteenth Century” interrogates the role that the epistolary form played in the construction, representation, and discipline of female gender expressions and sexualities across the eighteenth century. Working from the perspectives of queer theory, formal analysis, and literary history, this dissertation argues that...
Given directives such as the UN Global Goals targeting sustainable development, the research presented herein makes but a small contribution to the advancement of alternative energy technologies. Nevertheless, the present work was largely motivated to address specific points of intrigue within the thermoelectrics community. The general principles demonstrated, however, may...
Total synthesis of natural products provides an avenue for investigation of complex chemical scaffolds, not only delivering access to biologically impactful molecules but also lending a deeper understanding of their inherent chemical reactivity. Expansion of reaction methodology, optimization of biological activity, and absolute structural confirmation can all be accomplished via...
In this thesis, we study applications of the theory of perverse sheaves and their enhancements to problems in birational geometry. In the first application, we give positive results towards a conjecture of Batyrev about the nonnegativity of stringy Hodge numbers. In particular, we prove the nonnegativity of $(p,1)$-stringy Hodge numbers...
Cells are often precisely organized into patterns within developing tissues. This precision must emerge from biochemical processes within, and between cells, that are inherently stochastic. I investigated the impact of stochastic gene expression on self-organized pattern formation, focusing on Senseless (Sens), a key target of Wnt and Notch signaling during...
The variation of entropy in a family of dynamical systems is a natural indication of the bifurcations that the family undergoes. In the context of one-dimensional dynamics, Milnor's monotonicity of entropy conjecture (now a theorem of Bruin and van Strien) asserts that for polynomial interval maps with real critical points...
Phenotypic diversity underlies life as we know it–a variety of species, each with different roles, are essential for a fully functioning ecosystem just as a range of different crops is necessary to provide different nutritional value. Even within a single species, individual variation promotes diversity, allowing for adaptation to new...
Approximately 80-90% of individuals with Parkinson’s disease (PD) develop motor speech impairments, predominantly in the form of voice dysfunction. It is known that the motor symptoms of PD arise from degeneration of the dopamine producing neurons in the substantia nigra and dysregulation of basal ganglia motor pathways. It is also...
Soft matter is the field of science concerning soft and deformable materials: such as liquids, gels, and foams. Active matter is a sub-field of soft matter that considers systems that contain active agents or particles that consume energy for self-propulsion or to exert mechanical stress on the surrounding system. In...
In conventional data federations, a set of data providers each possess an autonomous database and collectively make the union of these databases available for querying by a client from a unified SQL interface. This setting however, provides no guarantees on data privacy or security. With my work, I consider a...
After the Second World War, two states claimed to represent the same nation: “China.” This work examines how the Kuomintang (KMT) and the Communist Party of China (CPC) competed to represent China and the international consequences of that competition. The CPC’s victory in the Chinese Civil War (1946-1949) led to...
With connected vehicle generated (CVG) information, traffic stream parameters become straightforwardly quantifiable, enabling traffic state characterization and examination over a variety of operational conditions. Since the observation is independent of any spatial restrictions and unaffected by queue buildup and discharge, CVG data offer more comprehensive, more reliable inputs to the...