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Hsp90 and Physiological Stress Are Linked to Autonomous Transposon Mobility and Heritable Genetic Change in Nematodes

Description:

Transposable elements (TEs) have been recognized as potentially powerful drivers of genomic evolutionary change, but factors affecting their mobility and regulation remain poorly understood. Chaperones such as Hsp90 buffer environmental perturbations by regulating protein conformation, but are also part of the PIWI-interacting RNA pathway, which regulates genomic instability arising from...

Keyword:

transposable elements, piRNAs, stress-induced mutagenesis, hsp90, genome stability, and evolution

Creator:

Steve Whyard, Jeremy C. Brownlie, and Calen P. Ryan

Owner:

Chris Diaz

Publisher:

Oxford University Press

Date Uploaded:

05/08/2017

Date Modified:

05/08/2017

Date Created:

2016-12-24

Resource Type:

Article

Alternate Identifier:

https://doi.org/10.1093/gbe/evw284