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-
- Description:
- Atrial fibrillation (AF) is the most common cardiac arrhythmia, and associated with increased risk for ischemic stroke and mortality. While the risk of stroke has been shown to be reduced with the use of oral anticoagulants like Warfarin, these medications are predictably linked with an increased risk of bleeding, and...
- Keyword:
- Multidimensional imaging, Atrial fibrillation, Unicuspid aortic valves, Magnetic Resonance Imaging, Cardiac MRI, and 4D flow MRI
- Subject:
- Medical imaging, Engineering, and Biomedical engineering
- Creator:
- Ma, Liliana Esther
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15025 and etdadmin_upload_723481
-
- Description:
- Humans have a remarkable ability to create stable walking patterns that can resist and recover from perturbations. Unfortunately, this ability is substantially impaired after a stroke, limiting mobility and contributing to a high fall rate. To facilitate gait training during post-stroke rehabilitation, clinicians often incorporate body-weight support (BWS) systems that...
- Keyword:
- Biomechanics, Gait, Stroke, and Stability
- Subject:
- Biomechanics, Physical therapy, and Biomedical engineering
- Creator:
- Dragunas, Andrew
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15636 and etdadmin_upload_831434
-
- Description:
- Like many diseases, atherosclerotic cardiovascular disease is driven by the activity of inflammatory cells. Using molecular imaging to target and analyze populations of inflammatory cells is one promising strategy to non-invasively assess atherosclerosis progression. However, current molecular imaging contrast agents are not suited for such targeted imaging applications. Nanomaterial-based strategies...
- Keyword:
- Nanoparticles, Targeted delivery, Drug delivery, Magnetic resonance imaging, and Nanomaterials
- Subject:
- Nanotechnology, Nanoscience, and Biomedical engineering
- Creator:
- Modak, Mallika
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15664 and etdadmin_upload_836754
-
- Description:
- Nanomaterials are broadly defined as materials that exhibit at least one dimension that is less than 1,000 nm. Encompassed within nanomaterials are a class of constructs known as nanocarriers, which are applied as delivery vehicles for both encapsulated and covalently bound payloads. Poly(ethylene glycol)-block-poly(propylene sulfide) (PEG-b-PPS) is an amphiphilic block...
- Keyword:
- PEG-b-PPS, Nanocarrier, MPS, Surface Functionalization, and Sustained Delivery
- Subject:
- Biomedical engineering
- Creator:
- Karabin, Nicholas Blaise
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14700 and etdadmin_upload_666953
-
- Description:
- Single-molecule localization microscopy (SMLM) has significantly stimulated the development of methods to quantitatively visualize and characterize biomolecules in vitro and in situ. SMLM is a class of super-resolution microscopy (SRM) techniques, which exploits the “on-off” switching of individual fluorescent molecules to estimate their location with nanometer precision and offers spatial...
- Keyword:
- quantitative imaging, spectroscopy, super-resolution microscopy, and single-molecule localization microscopy
- Subject:
- Biomedical engineering
- Creator:
- Davis, Janel Lesedi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15048 and etdadmin_upload_733040
-
- Description:
- We have a remarkable ability to perform complex, coordinated movements without much conscious effort. In addition to the computations required to generate commands for muscles, a key aspect of coordinated motor control is incorporating sensory feedback about the movement. One of the most important feedback routes is through proprioception, the...
- Keyword:
- reaching, somatosensory cortex, monkey, cat hindlimb, musculoskeletal model, and motion tracking
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Chowdhury, Raeed Hasan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14692 and etdadmin_upload_666011
-
- Description:
- In nature, materials with complex architectures are formed through hierarchical self-assembly. Therefore, the study and design of hierarchically assembling materials is important in producing materials that mimic biological structures and is a key challenge in biomaterials science and engineering. In articular cartilage, hierarchical assembly of extracellular matrix (ECM) components provides...
- Keyword:
- Peptide Amphiphile, Hierarchical Assembly, Self-Assembly, Biomaterials, Supramolecular Chemistry, and Cartilage Engineering
- Subject:
- Biomedical engineering
- Creator:
- Lewis, Jacob Alexander
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15237 and etdadmin_upload_763197
-
- Description:
- Nanocarriers are drug delivery vehicles that have at least one dimension at the nanoscale (10-9 m). Engineering the nanocarrier surface is a strategy for targeting drug delivery to specific cell types to enhance efficacy and minimize side effects. A useful analogy is to consider how the chassis of an automotive...
- Keyword:
- Targeted Drug Delivery, Nanotechnology, Nanocarrier Chassis, Immunomodulation, Protein Adsorption, and Glaucoma
- Subject:
- Biomedical engineering, Pharmaceutical sciences, and Materials Science
- Creator:
- Vincent, Michael Patrick
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15870 and etdadmin_upload_863441
-
- Description:
- Nanocarriers are nanometer-sized (1-1000 nm) structures capable of encapsulating cargo. This encapsulation can drastically alter the pharmacokinetic properties of the cargo, while also allowing for the rational design and engineering of the nanocarrier itself. Poly(ethylene glycol)-block-poly(propylene sulfide) is an amphiphilic diblock copolymer capable of self-assembling into diverse nanocarriers. The purpose...
- Keyword:
- anti-inflammatory, nanoparticle, copolymer, PEG-b-PPS, and flash nanoprecipitation
- Subject:
- Biomedical engineering and Biology
- Creator:
- Allen, Sean David
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14509 and etdadmin_upload_638353
-
- Description:
- Chromatin, a complex nuclear structure comprised of DNA, histones, RNA, and other nuclear proteins, is one of the most critical components within the cell because it houses the genetic information and its organization regulates important cellular functions, such as transcription, replication, and repair. Its structural organization is well understood at...
- Subject:
- Medical imaging and Biomedical engineering
- Creator:
- Gladstein, Scott
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14569 and etdadmin_upload_656834
-
- Description:
- Magnetic resonance imaging (MRI) is used widely and frequently in the clinical setting to image and diagnose patients. In addition to the anatomical scans that can be acquired using MRI, different kinds of physiological parameters, such as blood flow, can be obtained by utilizing pulse sequence, scan protocol and post-processing....
- Subject:
- Biomedical engineering
- Creator:
- Jeong, Yong Ik
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14483 and etdadmin_upload_628020
-
- Description:
- Coordinated movement relies on the precise and controlled activation of populations of motor units, which convert the commands of the nervous system into muscle forces. Motor unit firing patterns are often nonlinear and generated through the response to a combination of ionotropic excitatory and inhibitory commands, as well as metabotropic...
- Keyword:
- Motoneuron, Delta-F, Motor Unit, Aging, Stroke, and Persistent Inward Currents
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Hassan, Altamash Shamsul
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_843639 and http://dissertations.umi.com/northwestern:15718
-
- Description:
- Everyday tasks, such as putting on a jacket or reaching up to a shelf, often become more challenging for older adults. These tasks rely on the ability to generate three-dimensional torques about the shoulder and to adapt these torques across activities. Shoulder strength and muscle coordination impact shoulder torque production,...
- Subject:
- Biomedical engineering
- Creator:
- Baillargeon, Emma
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_764681 and http://dissertations.umi.com/northwestern:15278
-
- Description:
- Atrial fibrillation (AF) is the most common arrhythmia in adults in the United States. Despite its prevalence, the etiology of AF and its adverse effects are not completely understood, which has made treatment of AF difficult. However, left atrial (LA) fibrosis is associated with worsening and propagating AF. Additionally, research...
- Subject:
- Biomedical engineering
- Creator:
- Gunasekaran, Suvai
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/29/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_717382 and http://dissertations.umi.com/northwestern:14983
-
- Description:
- Fluorescence microscopy has become a widely used tool in many research areas. However, its spatial resolution, limited to 250 nm by the diffraction limit of light, has restricted direct observation of details of ultrastructural biology. In recent years, spectroscopic single-molecule localization microscopy (sSMLM), one of super-resolution imaging techniques, has been...
- Subject:
- Biomedical engineering
- Creator:
- Song, Ki-Hee
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_755276 and http://dissertations.umi.com/northwestern:15189
-
- Description:
- Nucleic acids such as DNA or RNA of various lengths and structures have a wide scope of functions as therapeutic entities compared to conventional drugs. For instance, native and modified forms of nucleic acids can be used for gene silencing, genome editing, gene replacement, immune system modulation, and theranostics. While...
- Keyword:
- RNA, DNA, nanoparticles, drug delivery, and lipids
- Subject:
- Biomedical engineering
- Creator:
- Sinegra, Andrew
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_845229 and http://dissertations.umi.com/northwestern:15759
-
- Description:
- End-stage renal disease, or kidney failure, can result from acute kidney injury or sustained kidney damage in the form of chronic kidney disease. As the prevalence of end-stage renal disease continues to rise, the gold-standard treatment—kidney transplantation—is increasingly restricted by the shortage of transplantable donor kidneys. Bioengineered kidney tissues may...
- Keyword:
- Regenerative Engineering, Glomerular Endothelial Cells, Biomaterials, Podocytes, Kidney Bioengineering, and Hydrogels
- Subject:
- Biomedical engineering and Bioengineering
- Creator:
- Su, Jimmy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14793 and etdadmin_upload_684137
-
- Description:
- Nucleic acids not only are the building blocks of life but also a class of attractive macromolecular therapeutics. However, the delivery of therapeutic oligonucleotides into cells has been a major challenge due to their large size and highly negatively charged backbone. Spherical nucleic acids (SNAs) are a class of emerging...
- Keyword:
- Drug delivery, Gene regulation, and Nanomedicine
- Subject:
- Chemical engineering, Biomedical engineering, and Materials Science
- Creator:
- Zhu, Shengshuang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_672179 and http://dissertations.umi.com/northwestern:14728
-
- Description:
- The dynamics of human joints are fundamental characteristic of the human motor system, and altered joint impedance can hinder mobility. Individuals with transtibial amputation typically experience slower and energetically costly gait, while individuals with chronic stroke experience persisting gait deficits arising from spasticity, hypertonia and paresis. Investigating joint impedance of...
- Keyword:
- System Identification, Stroke, Impedance, and Rehabilitation
- Subject:
- Biomechanics and Biomedical engineering
- Creator:
- Shorter, Amanda L
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15392 and etdadmin_upload_780328
-
- Description:
- Soft materials in nature are formed through programmed self-assembly of biomolecules to create complex architectures and optimized physical properties. It is therefore a key challenge in biomaterials science and engineering to understand the principles that govern the structure and properties of such materials, and the interactions between their different components....
- Subject:
- Biomedical engineering and Materials Science
- Creator:
- Sangji, Mohammad Hussain
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15536 and etdadmin_upload_816157
-
- Description:
- Bio-inspired materials have a distinct advantage over other materials by virtue of their mimicry of nature’s own products, which have been subjected to the inimitable tests of time and evolutionary pressure. Here we have taken instruction from natural nanostructures that are ubiquitous across the animal kingdom, namely high-density lipoproteins (HDL)....
- Keyword:
- self-assembly, high-density lipoproteins, nanoparticles, prostate cancer, and exosomes
- Subject:
- Biomedical engineering
- Creator:
- Henrich, Stephen E.
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/06/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15705 and etdadmin_upload_842037
-
- Description:
- Microfluidic technologies enable multi-tissue culture and precise control of media exchange and therefore have significant potential to create more complex in vitro models of reproductive systems, including endocrine cycles. However, microfluidic technologies have largely been applied to gamete-level culture in reproductive biology, with very little progress in organ-level culture. Herein...
- Keyword:
- Microfluidics, Oocyte, 3D Printing, Islet, Ovary, and Toxicity
- Subject:
- Biomedical engineering, Biology, and Obstetrics
- Creator:
- Rogers, Hunter Bradley
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14603 and etdadmin_upload_661219
-
- Description:
- The goal of the work reported here was to answer two important questions with regards to LTVV use for patients with ARDS: 1) How do we measure adoption? and 2) What are the drivers of provider adoption? To this end, I have demonstrated the influence of patient height, hypoxemia severity,...
- Keyword:
- acute respiratory distress syndrome, low tidal volume ventilation, network science, implementation science, and data science
- Subject:
- Medicine and Biomedical engineering
- Creator:
- Bechel, Meagan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/29/2020
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14975 and etdadmin_upload_716010
-
- Description:
- Motor planning is fundamental to the performance of everyday reaching movements. The influence of planning is not limited to voluntary movements but extends to involuntary movements initiated in response to sensory stimuli, such as postural perturbations applied to the arm. Stroke alters voluntary reaching and the involuntary response to perturbations,...
- Keyword:
- Reaching, Startle, Stroke, and Motor Planning
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Heckman, Rosalind Lauren
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_625731 and http://dissertations.umi.com/northwestern:14442
-
- Description:
- Maneuvering your limbs requires both accurate commands for how to move, and accurate feedback of their true movements. Conventional prosthetic arms currently lack this sense of proprioceptive feedback, which can make daily tasks difficult without close visual monitoring. Although studies have successfully provided artificial proprioceptive feedback to improve control, this...
- Keyword:
- myoelectric prosthesis, motor adaptation, and sensory feedback
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Earley, Eric Joseph
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_713001 and http://dissertations.umi.com/northwestern:14963
-
- Description:
- The shoulder is the most mobile joint in the human body, allowing for the execution of complex and athletic tasks. Unfortunately, such expansive mobility comes at a cost. The shoulder is prone to instability, or painful symptoms associated with increased humeral head translation, and dislocation. To prevent dislocations and maintain...
- Keyword:
- shoulder instability, joint stiffness, impedance, muscle reflex, and musculoskeletal modeling
- Subject:
- Biomechanics, Nanoscience, and Biomedical engineering
- Creator:
- Nicolozakes, Constantine
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15541 and etdadmin_upload_817085
-
- Description:
- The last decade has witnessed a rapid transformation in our understanding of the structure of chromatin, the nuclear complex of DNA and its structural proteins. While, barring mutations, the DNA sequence in each cell of the human body is the same, it is the structure of the chromatin complex that...
- Keyword:
- crowding, nucleus, and dynamics
- Subject:
- Biomedical engineering, Biology, and Biophysics
- Creator:
- Shim, Anne Rosati
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15565 and etdadmin_upload_818662
-
- Description:
- Optical microscopy is one of the most ubiquitous tools for functional imaging of biological phenomena. While relatively non-destructive to living organisms, light microscopy’s spatial resolution is diffraction limited, restricting the minimum resolvable features. On the other hand, high resolution techniques such as electron microscopy or STORM, have several orders of...
- Subject:
- Biomedical engineering
- Creator:
- Eid, Aya
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/06/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15612 and etdadmin_upload_827891
-
- Description:
- Transplantation is necessary and often the only viable treatment for many forms of end stage organ failure. While advances in immunosuppressive therapies have facilitated largely blocking acute rejection, 5-10 year post-transplant attrition rates have not significantly improved in the past 30 years. The predominant antigen facilitating the alloimmune response is...
- Subject:
- Immunology and Biomedical engineering
- Creator:
- Shah, Sahil Vijendra
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/06/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15715 and etdadmin_upload_843477
-
- Description:
- 4D Flow MRI is a phase-contrast magnetic resonance imaging method that enables direct measurement of velocities in three orthogonal directions throughout the heartbeat. This permits direct quantification of hemodynamic parameters, including flow, mean velocity, peak velocity, and pulsatility, for individual cerebral vessels. Despite ongoing research into neurovascular applications of 4D...
- Keyword:
- Arteriovenous malformation, Neurovascular, MRI, Flow imaging, and 4D Flow
- Subject:
- Medical imaging and Biomedical engineering
- Creator:
- Aristova, Maria
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15402 and etdadmin_upload_780813
-
- Description:
- Cancer progression is a complex process, leading to metastatic spread of primary tumor cells that colonize distant vital organs and mortality if not stopped. Since clinical strategies to stem this progression are still being developed, it is of great importance to detect this end stage metastatic spread as early as...
- Keyword:
- Tissue Engineering, Optical coherence tomography, Coral, Biomaterials, Light scattering, and Cancer detection
- Subject:
- Medical imaging, Biomedical engineering, and Zoology
- Creator:
- Spicer, Graham Lorne Cameron
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14594 and etdadmin_upload_660896
-
- Description:
- One method of cancer treatment is to thermally ablate (destroy) tumor masses using heat caused by electric current, or Joule heating. This particular modality is called radiofrequency ablation (RFA), due to the use of electric currents in the 100 kHz to 800 kHz frequency range. Computationally, RFA is simulated as...
- Subject:
- Biomedical engineering and Computer engineering
- Creator:
- Wang, Yearnchee
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14709 and etdadmin_upload_667884
-
- Description:
- Nanocarriers as structures with at least one dimension in the nanometer scale are capable of loading small molecule therapeutics that would otherwise have poor bioavailability, non- specific uptake, and off target effects. Polymeric nanocarriers can be modified to tune their chemical and biological behavior to better suit the intended application....
- Subject:
- Nanoscience, Biomedical engineering, and Polymer chemistry
- Creator:
- Frey, Molly Alexandra
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_855266 and http://dissertations.umi.com/northwestern:15814
-
- Description:
- Nanocarriers, structures with at least one dimension on the nanoscale (1-1000 nm), have been engineered for delivery of various cargoes. The shape and flexibility of nanocarriers are important parameters that influence their biological performance. Self-assembling polymeric filamentous nanocarriers, known as filomicelles (FM), are of great interest to nanomedicine due to...
- Keyword:
- filaments, nanoparticles, flash nanoprecipitation, flexibility, pi-stacking, and circulation time
- Subject:
- Nanotechnology, Nanoscience, and Biomedical engineering
- Creator:
- Li, Sophia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15821 and etdadmin_upload_856044
-
- Description:
- We perform many movements every day without much deliberation. However, moving can be seen as a form of decision-making since one of many possible movements must be selected and executed. The decision-making processes that underlie movements are influenced by various factors, including sensory perception, energetics, time, perceived rates of failure...
- Keyword:
- reticulospinal, looming, escape, hind brain, spinal cord, and decision
- Subject:
- Biomechanics, Biomedical engineering, and Neurosciences
- Creator:
- Bhattacharyya, Kiran
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_653282 and http://dissertations.umi.com/northwestern:14560
-
- Description:
- We rely on the properties of our skeletal muscles to traverse our world, interact with objects, and complete everyday tasks. The macroscopic properties of muscles that endow us with these abilities arise from the material properties of muscle fibers and the surrounding extracellular matrix (ECM), as well as how they...
- Keyword:
- Material Properties, Decellularization, Skeletal Muscle, Extracellular Matrix, and Ultrasound Shear Wave Elastography
- Subject:
- Biomechanics and Biomedical engineering
- Creator:
- Reyna, William Eric
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_773821 and http://dissertations.umi.com/northwestern:15352
-
- Description:
- Neurons are sensitive to the mechanical properties of their environment and show better growth, survival and differentiation when they are cultured in soft environments with mechanical properties similar to those of the brain compared to other tissues. Within the central nervous system (CNS), there is also a range of mechanical...
- Keyword:
- aza-glycine, Supramolecular, Mechanical properties, Hydrogels, Peptide amphiphiles, and Neurons
- Subject:
- Biomedical engineering, Chemistry, and Neurosciences
- Creator:
- Godbe, Jacqueline M
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15006 and etdadmin_upload_719165
-
- Description:
- Proprioception, or the sense of one’s body in space, provides critical feedback that the brain usesto generate controlled movements. When proprioceptive feedback is lost, people find it difficult to perform even basic motor tasks. Despite its importance, proprioceptive coding of single neurons in the cuneate nucleus (CN), the most peripheral...
- Subject:
- Biomedical engineering
- Creator:
- Versteeg, Christopher
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15841 and etdadmin_upload_859788
-
- Description:
- The role of nuclei nanoenvironment in cellular function has been a challenging problem in biology due to the lack of chromatin 3-dimension (3D) structure imaging/capturing techniques and theory connecting physical structure of chromatin to transcription. Recent studies on optical properties measurement on biological sample techniques, nanoscale imaging techniques and chromatin...
- Keyword:
- drug, transcription, and chromatin
- Subject:
- Biomedical engineering
- Creator:
- Wu, Wenli
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14527 and etdadmin_upload_639850
-
- Description:
- Despite improvements to diagnostics and treatment methods, colorectal cancer remains the second leading cause of cancer death in the United States. Colonoscopies, the gold standard for colorectal cancer screening, can significantly increase the patient’s chance of survival through early detection. However, colonoscopy cost, surgical complications, and patient bowel preparations limit...
- Subject:
- Biomedical engineering
- Creator:
- Winkelmann, James A
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14582 and etdadmin_upload_658977
-
- Description:
- Myoelectric pattern recognition-based upper limb prostheses measure electromyographic (EMG) signals from the residual limb and learn to identify muscle activity patterns that correspond to intended gestures. To train an accurate pattern recognition controller, it is essential that the training signals typify signals measured in real-world scenarios. When these conditions are...
- Subject:
- Biomedical engineering
- Creator:
- Teh, Yuni
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16046 and etdadmin_upload_900944
-
- Description:
- Bioelectronic devices at the biotic/abiotic interface face a number of key challenges that include device degradation when exposed to biological fluid, their elicited immune response due to mechanical mismatch, and poor signal transduction. Organic electronic materials and their devices, such as organic electrochemical transistors (OECTs) address these shortcomings. They can...
- Keyword:
- bioelectronics, Transistors, and Organic
- Subject:
- Biomedical engineering
- Creator:
- Rashid, Reem Basel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_896768 and http://dissertations.umi.com/northwestern:15998
-
- Description:
- Over the past decade, wearables have become pervasive in our lives. Healthcare wearables like a smartwatch continuously monitor personal health status and provide personalized feedback to motivate progress towards medically recommended goals. While present set of on-body electronics empowers users to visualize health status outside of clinic spaces, its traditionally...
- Subject:
- Biomedical engineering and Engineering
- Creator:
- Heo, Seung Yun
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_858088 and http://dissertations.umi.com/northwestern:15834
-
- Description:
- A stroke occurs when blood flow in the brain is impaired and often causes damage to corticospinal tract projections that control the muscles of the upper-extremity. Due to this damage, 50-70% of stroke survivors experience long-term upper-extremity functional deficits(Faria-Fortini, Michaelsen, Cassiano, & Teixeira-Salmela, 2011). These deficits result from motor impairments...
- Keyword:
- Biomechanical, Stroke, Strength, Neural, Weakness, and hemiparetic
- Subject:
- Biomedical engineering
- Creator:
- Garmirian, Lindsay
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14829 and etdadmin_upload_686135
-
- Description:
- Label-free assays, and particularly those based on the combination of mass spectroscopy with surface chemistries, enable high-throughput experiments of a broad range of reactions. However, these methods can still require the incorporation of functional groups that allow immobilization of reactants and products to surfaces prior to analysis. In this thesis,...
- Keyword:
- Microarray, Mass Spectrometry, SAMDI, Reactions, Surface chemistry, and Nanotechnology
- Subject:
- Biomedical engineering, Chemical engineering, and Chemistry
- Creator:
- Helal, Kazi Yasin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_719318 and http://dissertations.umi.com/northwestern:15011
-
- Description:
- Decisions in naturalistic environments usually feature delayed and uncertain outcomes that can only be reached after a sequence of actions are performed. For example, canonical stalking and pursuit strategies used by terrestrial predators often involve stages of concealment, pauses where the predator remains motionless, and high speed chase sequences. The...
- Keyword:
- Ecology, Evolution, Computational Neuroscience, and Decision Making
- Subject:
- Ecology, Biomedical engineering, and Neurosciences
- Creator:
- Mugan, Ugurcan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15318 and etdadmin_upload_769384
-
- Description:
- A one-time, unilateral injury to the developing brain can interrupt the typical process of development and result in motor impairments that evolve over the course of the whole life-span. The timing of injury relative to neural development has implications for the continued refinement of the nervous system and the descending...
- Keyword:
- mirror movement, pediatric hemiplegia, corticospinal tract, cerebral palsy, flexion synergy, and reaching
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Hill, Nayo Marel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_792769 and http://dissertations.umi.com/northwestern:15452
-
- Description:
- Radiofrequency ablation is a minimally-invasive treatment method that aims to destroy undesired tissue by exposing it to alternating current in the 100 kHz to 800 kHz frequency range and heating it until it is destroyed via coagulative necrosis. Ablation treatment is gaining momentum especially in cancer research, where the undesired...
- Keyword:
- Hardware Design, Cancer Therapy, Integrated Circuit, Ablation, Machine Learning, and Ensemble Learning
- Subject:
- Artificial intelligence, Biomedical engineering, and Electrical engineering
- Creator:
- Besler, Emre
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15432 and etdadmin_upload_786973
-
- Description:
- Nanoparticles are nanometer scale (1-1000 nm) structures capable of encapsulating a diverse range of cargoes. Encapsulation of a cargo can drastically alter its pharmacokinetics, cytotoxicity, and biodistribution while allowing for informed and rational design of the nanoparticle itself. Poly(ethylene glycol)-block-poly(propylene sulfide) (PEG-b-PPS) is an amphiphilic diblock co-polymer able to self-assemble...
- Keyword:
- Nanoparticles, Latrunculin A, Glaucoma, and Targeted Delivery
- Subject:
- Biomedical engineering and Nanotechnology
- Creator:
- Stack, Trevor
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_815566 and http://dissertations.umi.com/northwestern:15530
-
- Description:
- Found in 1-2% of the population, bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease and is associated with increased risk of aortic valve dysfunction and aortic disease. Current treatment is focused on surgical intervention either after the development of symptomatic aortic stenosis/regurgitation or aortic diameter thresholds. However,...
- Keyword:
- MRI, Aorta, and 4D flow
- Subject:
- Medical imaging and Biomedical engineering
- Creator:
- Scott, Michael Baran
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_817047 and http://dissertations.umi.com/northwestern:15540
-
- Description:
- Chromatin is the biological material that packages our genetic information. In humans, 2 meters of linear DNA is compacted into an approximately 6 μm nucleus. Our DNA is transcribed into RNA, which is then translated into proteins. Cellular phenotype, the composite of all cellular functions, is defined by the entire...
- Keyword:
- Computational Modeling, Nanoimaging, Genomics, Chromatin, and Biophysics
- Subject:
- Biomedical engineering
- Creator:
- Virk, Ranya Kaur Aphrodite
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_924911 and http://dissertations.umi.com/northwestern:16197
-
- Description:
- The current view in neuroscience holds that the brain, together with its sensory and motor structures and the environment, form a closed-loop system – a sensorimotor loop – in which the brain receives information from the environment and converts it into a motor response while simultaneously making predictions about future...
- Subject:
- Computer science, Biomedical engineering, and Neurosciences
- Creator:
- Zweifel, Nadina Olivia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16198 and etdadmin_upload_925059
-
- Description:
- Polymer and polymer/ceramic composites known as bone cements are commonly used in musculoskeletal reconstructive surgeries where bone tissue fixation, reinforcement, or void filling may be needed. Polymethylmethacrylate, PMMA, was the initial (and currently only) FDA-approved bone cement for bone-void filling applications yet faces many inherent material-based challenges that impacts its...
- Keyword:
- Hydroxyapatite, Polymethylmethacrylate, V70, Vertebral Body Fractures, Citrate-based biomaterials, and Bone Cement
- Subject:
- Materials Science, Biomedical engineering, and Polymer chemistry
- Creator:
- Huddleston, Samantha
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16143 and etdadmin_upload_915696
-
- Description:
- Nucleic acid therapeutics can be drug molecules with high programmability, minimal off-target effects, and the capability to address “undruggable” targets for diseases. In addition, each time a new drug is needed, one needs to only change the sequence as opposed to finding an entirely new structure. One nucleic acid type...
- Keyword:
- nanoparticle, structure-function, RNAi, spherical nucleic acid, siRNA, and gene therapy
- Subject:
- Pharmaceutical sciences, Nanotechnology, and Biomedical engineering
- Creator:
- Vasher, Matthew Kuo
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16319 and etdadmin_upload_938909
-
- Description:
- Before initiating a walking movement, the central nervous system forms a motor plan, a set of motor commands predicted to accomplish task-specific goals. To be effective, motor plans must be continually updated to consider an ever-changing external environment. Despite being an inherent part of walking, how the nervous system adapts...
- Keyword:
- Uncertainty, Motor Learning, Adaptation, Motor Control, Gait, and Center of Mass
- Subject:
- Physical therapy and Biomedical engineering
- Creator:
- Bucklin, Mary Ann
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16185 and etdadmin_upload_922879
-
- Description:
- Persons with spinal cord injuries can use state-of-the-art brain-computer interfaces to control robotic arms. Despite this high-tech solution, their movements are slow and imprecise, much like those made by individuals who have lost proprioception, the sense of body position and movement. Intracortical microstimulation (ICMS) used to reactivate neural circuits in...
- Keyword:
- prosthetic, stimulation, proprioception, and sensory
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Sombeck, Joseph T
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_917097 and http://dissertations.umi.com/northwestern:16157
-
- Description:
- Vimentin intermediate filaments (VIFs) provide mechanical integrity to cells and serve as markers of tissue origin and cell differentiation. Several non-mechanical roles for vimentin have recently been reported, including regulation of key pathways that control cell growth, cell signaling, and cell motility. Here, I present the role of vimentin in...
- Subject:
- Biomedical engineering
- Creator:
- Berr, Alexandra Lauran
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16237 and etdadmin_upload_927939
-
- Description:
- The physical structure of chromatin has recently emerged as a key contributor to genome regulation and cellular function. Chromatin packing dictates the conformation of the 2-meter-long DNA polymer within the ~10 μm cell nucleus. This conformation can influence gene function by regulating the accessibility of molecular regulators to DNA, altering...
- Subject:
- Biomedical engineering
- Creator:
- Agrawal, Vasundhara
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_981488 and http://dissertations.umi.com/northwestern:16492
-
- Description:
- Wireless power strategies are critical to system level implementation of bio-integrated devices. To achieve mechanically robust, manufacturable systems, batteries are often integrated as an on-board power source to support sensing, wireless communication and signal conditioning. Unfortunately, most sources of battery power use hazardous and environmentally harmful materials, which frustrate incorporation...
- Subject:
- Chemistry, Biomedical engineering, and Materials Science
- Creator:
- Huang, Ivy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_934213 and http://dissertations.umi.com/northwestern:16294
-
- Description:
- Cancer has long been the second-leading cause of death in the United States and represents the leading cause of death in midlife (age 40-60). While the prognosis for many cancers has vastly improved over the last thirty years, many cancers remain elusive due to the late-onset of symptoms, the specific...
- Keyword:
- Breast Cancer, Antibodies, Protein Switch, Machine Learning, and Cell Patterning
- Subject:
- Biomedical engineering
- Creator:
- Sykora, Daniel Joseph
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_936187 and http://dissertations.umi.com/northwestern:16305
-
- Description:
- Bio-integrated electronics with advanced monitoring capabilities have garnered considerable interest as a means of expanding patient care beyond traditional hospital and clinic settings. These mechanically soft microsystems, many of which are bioresorbable and wireless, have the potential to replace bulky, rigid, and wired medical technologies by matching or exceeding their...
- Keyword:
- Injectable Electronics, Electromagnetics, Engineering Modeling, Bioresorbable Pacemakers, Mechanics, and Skin-Integrated Electronics
- Subject:
- Mechanical engineering, Electromagnetics, and Biomedical engineering
- Creator:
- Avila, Raudel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_970258 and http://dissertations.umi.com/northwestern:16445
-
- Description:
- Shoulder (glenohumeral joint) osteoarthritis causes pain, limits daily activities, and frequently requires joint replacement surgery. In shoulder osteoarthritis, the glenoid bone surface erodes in one of two ways: symmetrically (concentric deformity) or asymmetrically (eccentric deformity). Shoulder replacements in patients with eccentric deformities fail and require additional, revision surgery more often...
- Keyword:
- Shoulder osteoarthritis, Arthroplasty, and Rotator cuff
- Subject:
- Biomedical engineering and Biomechanics
- Creator:
- Coats-Thomas, Margaret Sarah
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16136 and etdadmin_upload_913153
-
- Description:
- In environments ranging from natural ecosystems to living organisms, small molecule signals and nanoscale forces communicate important information regarding chemical contamination and pollution, pathogenesis, and physical stressors. As these stimuli are often well below detection limits for our own senses, we depend on biosensing technologies to monitorthem. Many biosensors operate...
- Keyword:
- Riboswitch, Lipid vesicle, Biosensor, and Membrane
- Subject:
- Biomedical engineering
- Creator:
- Boyd, Margrethe
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16042 and etdadmin_upload_900859
-
- Description:
- Islet transplantation is a therapy in which insulin-producing beta (β) islet cells are infusedinto the liver via the portal vein to restore glycemic control. This therapy is beneficial for patients suffering from chronic pancreatitis or type I diabetes. However, islet transplantation is not widely implemented due to the instant blood-mediated...
- Subject:
- Biomedical engineering
- Creator:
- Burke, Jacqueline Alexis
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_878166 and http://dissertations.umi.com/northwestern:15918
-
- Description:
- Each neuron in the primary motor cortex (M1) is like a musician in an orchestra, contributing to a larger harmony under the constraint of a “neural manifold”—a geometric score describing the correlated signals produced by the neural musicians that drive movement. Despite the widespread recognition of the importance of M1...
- Keyword:
- motor control, neural manifolds, brain-computer interface, machine learning, and neural networks
- Subject:
- Neurosciences and Biomedical engineering
- Creator:
- Altan, Ege
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16658 and etdadmin_upload_1001502
-
- Description:
- Ankle sprains are the most common musculoskeletal injury. After an ankle sprain, about 40% of individuals develop Chronic Ankle Instability (CAI), resulting in recurrent sprains, the ankle giving way, or feelings of instability. Most sprains occur due to excess inversion of the ankle. Frontal-plane ankle stiffness quantifies the ankle’s ability...
- Subject:
- Biomedical engineering and Biomechanics
- Creator:
- Villamar, Zoe Dahlia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16668 and etdadmin_upload_1002685
-
- Description:
- Stairs and curbs often present as an exhausting environmental barrier for individuals with bilateral cerebral palsy (CP) due to their lower limb motor impairments. Indeed, performance in stair-climbing in this population has a higher correlation with disruption of mobility than walking. Community members affected by CP consider impaired mobility a...
- Subject:
- Physical therapy, Biomedical engineering, and Biomechanics
- Creator:
- Goyal, Vatsala
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16701 and etdadmin_upload_1010522