Triplet excited state chemistry has enabled a range of important organic transformations by accessing reaction pathways inaccessible to photoredox chemistry. Such photoreactions are triggered by triplet photosensitizers, which absorb visible-light photons and transfer the energy to the substrate or to a co-catalyst through triplet-triplet energy transfer (TT EnT). The most...
Graphene oxide (GO) is a heavily oxidized version of graphene, which is often made by oxidative chemical exfoliation from graphite powders. The reaction decorates the graphene sheets with oxygen-containing functional groups including hydroxyl and epoxide groups on the basal plane, as well as carboxyl groups on the edge, rendering the...
This dissertation studies the real effects of firms’ financing decisions as well as the economics consequences of bias in fair value prices of corporate bonds. The first chapter examines the impact of compliance with changes in mandated financial reporting on corporate financing and investment decisions. I employ the recent implementation...
The commitment of resources to coaching almost always occurs in interaction with other district-wide efforts to improve instruction. Given this probable situation, it’s concerning that the field lacks the ability to provide guidance regarding how coaches might reasonably be integrated within overall plans for the coordination and improvement of instruction....
In the United States, allergic disease affects approximately 60 million people and impacts more people every year. While prevalence of allergic disease has steadily increased, there has concurrently been an increase in rates of metabolic syndrome—characterized by increased abdominal girth, decreased sensitivity to insulin, and higher levels of circulating blood...
The past decade has seen the rapid progress of deep learning, which becomes a game-changing technique in different data-intensive domains, with the availability of large scale data, cost-effective computing hardware and more advanced learning theory and algorithms. Despite of the rapid progress of deep learning methods in daily-life applications, such...
The goal of this thesis is to develop an experimental setup to evaluate and analyze the effect of crack-parallel stress on the fracture response of materials. In standard fracture test configurations, the crack-parallel normal stress is negligible. However, a new type of experiment, briefly named the gap test, revealed that...
Automated driving has become a very popular topic in the recent years and is becoming more and more of a reality. In this new trend, High Definition (HD) maps play an important role in many ways that will provide a safer and more efficient driving experience, especially in terms of...
The retina does not act as a simple camera, rather visual information goes through multiple layers of processing before it reaches the brain. Retinal ganglion cells (RGCs) are the output neurons of the retina and process visual information in the retina and then project into the brain. There are over...
Mechanosensation is an essential behavior for cellular health that depends on the interactions between the plasma membrane and stretch-activated ion channels. To date, a few studies have measured the effect of membrane composition on protein behaviors from folding to function. However, the relationship between membrane mechanical properties and these behaviors...
With the increasing demand for customized products, rapid prototyping, and small-batch production, incremental sheet forming (ISF) is gaining ever-growing attention. The potential of ISF to produce parts without the use of geometry-specific dies has revolutionized the sheet forming processes. Despite its promising characteristics, ISF thus far has not been extensively...
Membrane contact sites (MCSs) facilitate communication and organization of organelles that contribute to fundamental cellular processes. It has become increasingly appreciated how extensive and essential MCSs are for cellular health, and this field is rapidly growing. We use budding yeast as a model system to study the mechanisms of how...
This dissertation consists of three chapters on empirical industrial organization. The first chapter explores how a seller uses a public reserve price to signal her private info about the object’s value to the bidder. The second chapter studies how a behavioral consumer preference called “price reference effect” could overturn the...
Chapter 1. Undergraduate Gender Diversity and Direction of Scientific Research (with Francesca Truffa) Can diversity lead to greater research focus on populations underrepresented in science? Diverse researchers can bring new questions and perspectives, but exposure to diversity may also inspire scientists, regardless of demographic identity, to pursue new topics. This...
Does race matter globally, beyond national and regional contexts? If yes, then how exactly? I argue that race matters globally and develop an account for understanding that significance. I call the account “global racial capitalism.” In chapter 1, I offer background to motivate and defend the thesis that race matters...
CD99-Like 2 (CD99L2) is a 52 kDa type I glycoprotein expressed on leukocytes and endothelial cells as well as other cell types in mice. It is related to CD99, although it shows only 32% sequence identity. CD99L2 has been shown to play a role in leukocyte extravasation in mice under...
In this dissertation, we study the birational geometry of log pairs over the field of complex numbers, with an emphasis on the positivity properties of log pairs and their applications. First, we study the nonvanishing conjecture in the minimal model program. We prove the nonvanishing conjecture for uniruled log canonical...
In the first Chapter of this Dissertation, I develop an integrated reasoning model of expectations formation to describe how people learn the effects of novel macroeconomic policies. My model of expectations has two key elements. First, people have a limited ability to understand the general-equilibrium effects of a new policy....
Modern data sets are increasingly vast, not only in the number of samples, but also in the number of measurements, or features, that they contain. This high-dimensionality poses a unique set of problems for data analysis due to a set of phenomena known as ``the curse of dimensionality.'' This thesis...
The successful isolation of graphene marked the advent of two-dimensional (2D) materials. Their atomically thin structures enable unprecedented electrical, optical, and mechanical properties, which have triggered significant research interests in the past decade. For instance, they are promising candidates for the fabrication of flexible electronics, biological sensors, battery electrodes, and...
In this dissertation, I assert that a contradictory aesthetic has remained and been reborn in the U.S. daytime soap opera through time and technology; I call this the “everyday implausible.” Using textual analysis and archival research, I follow this genre from its beginnings on radio, through its move to television...
A prominent cause of premature ovarian insufficiency (POI) is gonadotoxic cancer therapies, which deplete the ovarian reserve of follicles, oocytes, and hormone-producing cells. Current fertility preservation methods include the removal and cryopreservation of ovarian tissue prior to gonadotoxic treatment. This cryopreserved tissue can be transplanted back and has been found...
Chapter 1 proposes and tests a model where a country aligns with a foreign power to obtain its support and reduce its geopolitical risks, which also depend on the country's exposure to the other foreign powers. We show that the country's alignment with a given foreign power is increasing in...
In the wake of environmental catastrophe, active intervention is needed to heal trauma, resist erasure, and navigate changing communities. Focusing on New Orleans after the federal levee failures following Hurricane Katrina, this dissertation looks across a diverse mix of case studies to theorize how communities utilize performance to navigate mass...
Between the 1880s and the 1980s, typography mutated from an entirely manual, craft-based practice to a comprehensively mechanized, then a fully digitized one. With the arrival of Apple’s Macintosh computer in 1984, the graphic design profession found itself in the midst of a deep transformation of its tools, techniques, and...
Skeletal muscle is a highly sexually dimorphic tissue, with males and females exhibiting differences in muscle size, gene transcription, and metabolism. This thesis describes two models wherein males and females responded to an intervention with the same physiological adaptation but through two distinct mechanisms. In the first model, mice of...
Integrating the selective reconstruction of the past with an imagined future, narrative identity is a person’s internalized and evolving story of the self, functioning to provide life with some degree of meaning, purpose, and temporal coherence (McAdams & McLean, 2013). Moreover, narrative identity has been found to be associated with...
ABSTRACT This dissertation moves work on school discipline into the digital era by filling a gap in the literature which has largely ignored how data from digital student ecosystems are mined and processed by school authority. My dissertation interrogates the role youth of youth online behavior in school discipline decision-making....
Yugoslav wartime television news often conformed to the demands of the political regimes. Informed by this knowledge, scholars have argued that TV as a medium incited and legitimized the wars by fostering ethnonationalist ideologies. Using archival and textual analysis, this project examines how television reacted to the political constraints imposed...
RAS is one of the most frequently mutated oncogenes in cancer with ~30% of all human tumors harboring a mutation in either HRAS, NRAS, or KRAS isoforms. Despite countless efforts for the development of small molecule inhibitors for RAS, it remains an elusive target in the clinic. Here I demonstrate...
Over the past decade, concepts and expressions derived from Black feminist theory, a line of intellectual thought historically produced from Black women’s unique lived experiences that asks us to consider how one’s material realities are co-constituted by multiple, interlocking systems of the oppressed, have traveled into the public sphere through...
Market growth is an important goal for consumer businesses, often leading to lower marginal cost, higher operational efficiency, and larger assortment size - all of which help achieve dominance over competition. Yet, retailers and manufacturers alike should carefully manage their supply chains to sustain growth in customer base and extract...
Rocky exoplanets are indicated to be common in the galaxy. Future instruments including the {\it James Webb Space Telescope} (JWST), high resolution ground-based spectrographs, and direct imaging missions for under consideration by the 2020 Decadal Survey on Astronomy and Astrophysics are poised to unlock the atmospheres of habitable zone planets...
Art has been tied to scientific and technological advancements throughout history, providing methods and mediums for communication, expression, and exploration. Art is a dialogic domain that evolves with the technological advances in society–incorporating technology and computational tools to create new genres of art. We live in an increasingly computational and...
Using the context of the oil and natural gas boom of North Dakota and Montana brought on by advances in hydraulic fracturing technology, this dissertation studies how changing economic conditions affect basic social well-being in a rural setting. Using methods of causal inference, specifically difference-in-differences regressions and comparative interrupted time-series...
Otoacoustic emissions are currently used for various clinical purposes; however, stimulus frequency otoacoustic emissions (SFOAEs) evoked using a single one are not utilized clinically due to uncertainties regarding their generation mechanism, their spatial source(s) in the cochlea, and their susceptibility to various cochlear insults, particularly in humans. Over the years,...
Thermoelectric devices utilize semiconducting n-type and p-type thermoelectric materials to convert heat into electricity. Despite their promise for deep space power generation or waste heat recovery, most high-performing thermoelectric materials reported in literature are absent in practical applications - partially due to inconsistent synthesis and poor mechanical performance. This work...
Facts are not enough! The more recent wave of science communication practices have been advocating for the death of the deficit model of science communication. This model notes that by possessing sufficient information, individuals will change their attitude and behavior to align with scientific facts. However, recent research has shown...
All animals purposefully navigate feature-rich environments: while exploring, in search of vital resources of food and water, finding mates, and patrolling and marking habitats. During these complex behaviors, continuous analogue input information from peripheral sensory organs guides discrete and digital sequential motor output; accordingly, each action is informed, modulated, or...
This thesis revisits classic optimal tax theory, recognizing that most people live in multi-person households. We derive optimal tax schedules for married agents, seriously taking the distinction between interpersonal and interhousehold inequality. After showing how individual-oriented utilitarianism typically leads to a misalignment between the households’ and the government’s objectives, which...
I set up a disagreement model where traders not only have different interpretations of a public signal that conveys information of a stock, but are also uncertain about the information quality of others' interpretations. The model along with traders being ambiguity-averse predicts a positive relation between investor disagreement (ID) and...
This dissertation is a culmination of work spanning several modes of travel, multiple datasets, and different contexts. Because the proliferation of new mobility services disrupted the transportation ecosystem, I aim to understand travel behavior and investigate how new and traditional modes intermingle. I focus my attention on Mobility-on-Demand which encompasses...
The cerebellar cortical system is an extensively studied circuit which is critical for motor learning. While multiple monoamines, such as norepinephrine and serotonin, modulate cerebellar cortical output, the mechanistic details of dopaminergic signaling in the cerebellum remain poorly understood. Additionally, neuronal cell types residing within the cerebellum remain relatively under-characterized....
This dissertation consists of three chapters that each study the interaction between government policy and real estate markets. All three chapters are connected by a broad interest in renters, landlords, and rental markets. Chapter 1 investigates the relationship between place-based policies and real estate and rental markets empirically by studying...
Macrophages are innate immune cells that are traditionally thought to be specialists in phagocytosis. More recent evidence suggest that macrophages reside in nearly every organ and readily adapt to local microenvironmental signals, leading to highly plastic phenotypes across and within tissues. Therefore, rather than treating it as a homogenous cell...
Children acquire linguistic competence via social interactions with adults and learn to converse in accordance with the norms of their communities. The present dissertation examined the communicative patterns of Thai-English bilingual mothers and children in their two languages, as well as compared the bilinguals’ conversations to each of their monolingual...
This dissertation provides an introduction to the diffraction and scattering theory for the Aharonov--Bohm Hamiltonian with one or multiple poles on $\mathbf{R}^2$. It shows the propagation of diffractive singularities of the wave equation with the magnetic Hamiltonians with singular vector potential, which is related to the so-called Aharonov--Bohm effect. Based...
As the interest in rational synthesis for solid-state materials accelerates, there is an urgent need to understand the design principles concealed within these reactions. In situ material synthesis provides such an avenue to not only uncover these assembling rules, but also for finding new materials even in seemingly familiar phase...
The three essays composing this dissertation are unified by their focus on the macroeconomic aspects of economic development. In Chapter one titled "Land Property Rights, Financial Frictions, and Resource Allocation in Developing Countries'', I study the effects of weak land property rights and limited access to finance on aggregate productivity...
Part I: Evaluating the relationship between Crosslink Kinetics and Thermodynamics with the hydrogel mechanics. The past two decades have witnessed a surge of applications built upon dynamic covalent chemistry (DCC), both attributed to the scope of developed reactions as well as their modularity.1-3 These reactions have comparable strengths to their...